D.I. KOSHELEV

«Russian Eye and Plastic Surgery Center» of the Russian Federation Health Ministry, Ufa, Russian Federation

  Contact details:

Koshelev D.I. – Cand. Biol. Sc., Associate Professor, Head of the Laboratory of Neurophysiology of Vision

Address: 67/1 R. Zorge St., Ufa, Russian Federation, 450075, tel.: +7 (347) 293-42-11, e-mail: koshelev_d@mail.ru

 To assess the effectiveness of combined analysis of visual evoked potentials (VEP) to the reversal checkboard pattern and parameters of fixational eye movements in children with impaired central vision.

Materials and methods. Visual evoked potentials and fixational eye movements were recorded in subjects with normal vision, with amblyopia, nystagmus and dysfunction of the central retina. VEP was registered binocularly and monocularly from the distance of 1 meter. A sequential series of checkboard patterns with a check size of 240, 96, 48, 24 and 12 arcminutes were used as a stimulus. The registration of eye movements during fixation was performed using an MP-1 microperimeter with a spatial resolution of 6 arcminutes and a temporal resolution of 25 Hz.

Results. Combined analysis of VEP and eye movements demonstrated highly informative results in the assessment of central vision pathology in children. The main parameters in evaluation of the VEP series were the character of changes in the amplitude-latency parameters of the N75-P100 complex and the size of the pattern checks causing a response of the maximum amplitude. The most important characteristics of eye movements were: position of the fixational area relative to the fovea, amplitude and rhythm of eye movements.

Conclusion. It was shown that using the combined data of VEP and the registration of fixational eye movements allows assessing the potential possibilities and identify inefficiently functioning parts of the visual system. Based on these data, it is possible to carry out objective monitoring of visual functions and to plan an effective program for the development of a child’s vision, including operational and functional treatment.

Key words: visual evoked potentials, fixational eye movements, monitoring of visual functions.

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