A.V. LISITSA, S.K. SOODAEVA, I.A. KLIMANOV, A.V. AVERYANOV
Federal Scientific and Practical Center for specialized types of health care and medical technology of the Federal Medical and Biological Agency of Russia, Moscow
Pulmonology scientific and research institute of the Federal Medical and Biological Agency, Moscow

Lisitsa Alexander Valerevich
Candidate of Medical Science, Head of the Department of Clinical Research FSBI Federal Scientific and Practical Center for specialized types of health care and medical technology of the Federal Medical and Biological Agency of Russia, Russia
28 Orekhovyy blvd., Moscow 115682
tel. (499) 255-78-65, e-mail: afox03@mail.ru

The article highlights a wide range of problems related to application of phospholipid drugs and their liposomal forms in treatment of internal diseases. The main emphasis is made on pulmonology aspect of using the abovesaid drugs. The article describes the collaborative mechanisms of drugs on basis of phosphatidylcholine and cellular system «oxidants-anti-oxidants» under normal and pathological conditions. Is considered the natural antioxidant activity at the cellular level and put forward reasonable suggestions on practical synergies between antioxidants and phospholipids.

Key words: phospholipids, oxidative stress, membranes reparation, oxidant-antioxidant cell activity, respiratory diseases.

 

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