Two cases of neonatal fungal sepsis caused by Candida krusei
Kh.S. KHAERTYNOV1, V.A. ANOKHIN1, S.A. LYUBIN2
1Kazan State Medical University, Butlerov St., 49, Russian Federation, 420012
2City Children’s Hospital, Dekabristov St., 125a, Russian Federation, 420034
Khaertynov Kh.S. — Cand. Med. Sc., Associate Professor of the Department of Children’sInfectious Diseases, tel. +7-903-342-96-27, e-mail: khalit65@rambler.ru
Anokhin V.A. — D. Med. Sc., Professor of the Department of Children’s Infections, tel. (843) 267-81-00, e-mail: anokhin56@mail.ru
Lyubin S.A. — Head of the Neonatal Intensive Care Unit, tel. +7-903-341-87-20, e-mail: Lubins65@mail.ru
The authors describe two cases of neonatal fungal sepsis caused by Candida krusei in children born with extremely low weight. Inonecase, thediseaseended with a recovery,intheother the outcome was lethal.The risk factors for Candida sepsis in neonatesare considered.
Key words: newborns, fungal sepsis, treatment.
REFERENCES
1. Barton M., O’Brien K., Robinson J.L. et al. Invasive candidiasis in low birth weight preterminfants: risk factors, clinical course and outcomein a prospective multicenter study of cases andtheir matched controls. BMC. Infectious Diseases, 2014, vol. 14, p. 327.
2. Perlroth J., Choif., Spellberg B. Nosocomial fungal infections: epidemiology, diagnosis, and treatment. Medical Mycology, 2007, vol. 45, pp. 321-346.
3. Chow B., Linden J.R., Bliss J.M. Candida parapsilosisand the neonate: epidemiology, virulenceand host defense in a unique patient setting. Expert Rev Anti Infect Ther., 2012, vol. 10, no. 8, pp. 935-946.
4. Huang Y.C., Li C.C., Liu T.Y. et al. Association of fungal colonization and invasive disease in very low birth weight infants. Pediatr Infect Dis Jr., 1992, vol. 17, pp. 819-22.
5. Kaufman D., Fairchild K.D. Clinical Microbiology of Bacterial andFungal Sepsis in Very-Low-Birth-Weight Infants. Clin. Microbiol. Rev., 2004, vol. 17, no. 3, p. 638.
6. Benjamin D.K., Stoll B.J., Gantz M.G. Neonatal candidiasis: epidemiology, risk factors, and clinical judgment. Pediatrics, 2010, vol. 126, no. 4, pp. 865-873.
7. Benjamin D.K. Neonatal Candidiasis and neurodevelopmental outcomes. Pediatrics, 2006, vol. 117, pp. 84-92.
8. Lee J.H., Hornik C.P., Benjamin D.K., Herring A.H. et al. Risk Factors for Invasive Candidiasis in Infants >1500 g Birth Weight. Pediatr Infect Dis J., 2013, vol. 32, no. 3, pp. 222-226.
9. Amaral-Lopes S., Moura A. Neonatal fungal sepsis by Candida krusei: A report of three cases and a literature review. Medical Mycology Case Reports, 2012, vol. 1, pp. 24-26.