Thromboembolic complications related to the use of assisted reproductive treatment. Ovarian hyperstimulation syndrome
V.O. BITSADZE, S.V. AKINSHINA, M.D. ANDREEVA, A.D. MAKATSARIYA
I.M. Sechenov First Moscow State Medical University, 8 Trubetskaya St., bld.2, Moscow, Russian Federation 119991
Akinshina S.V. — Candidate of Medical Science, research associate of the Department of Obstetrics and Gynaecology of Public Health faculty, 62 Zemlyanoy Val St., bld.1., Moscow, Russian Federation 109004, tel. +7-903-238-80-48, e-mail: gemostasis@mail.ru
Bitsadze V.O. — D.Med.Sc., Professor of the Department of Obstetrics and Gynaecology of Public Health faculty, 62 Zemlyanoy Val St., bld.1., Moscow, Russian Federation 109004, tel. +7-926-231-38-29, e-mail: gemostasis@mail.ru
Andreeva M. D. — Candidate of Medical Science, doctoral candidate of the Department of Obstetrics and Gynaecology of Public Health faculty, 62 Zemlyanoy Val St., bld.1., Moscow, Russian Federation 109004, tel. +7-918-388-61-11, e-mail: gemostasis@mail.ru
Makatsariya A.D. — D.Med.Sc., Professor, corresponding member of RAMS, Head of the Department of Obstetrics and Gynaecology of Public Health faculty, 62 Zemlyanoy Val St., bld.1., Moscow, Russian Federation 109004, tel.+7-903-728-08-97, e-mail: gemostasis@mail.ru
The article discusses the risk factors for thromboembolic complications before using assisted reproductive treatment. Herewith is evaluated the role of acquired and genetic defects of blood coagulation, as well as systemic inflammation response syndrome. Special focus is on the pathogenesis and clinical ovarian hyperstimulation syndrome. Personal and international experience in the prevention of thrombosis in patients enrolled in the IVF program is described.
Key words: thrombosis, reproductive technologies, acquired and genetic thrombophilia, ovarian hyperstimulation syndrome.
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