The use of elastin biomaterial in the reconstructive surgery of orbit walls
R.T. NIGMATULLIN, R.Z. KUTUSHEV
The Russian Eye and Plastic Surgery Centre of the Russian Federation Health Ministry, 67/1 Zorge Str., Ufa, Russian Federation, 450075
Nigmatullin R.T. ― D.Med.Sc., Deputy Director General for Science, tel. (347) 224-68-03, e-mail: nigmatullinr@mail.ru
Kutushev R.Z. ― Head of the Ophthalmological Department, tel. (347) 224-68-19, e-mail: rinat-dok@yandex.ru
The article presents data on the experimental transplantation with elastin biomaterial (patent №2440148). The purpose of the experiment was to replace the defects of the orbital roof and ocular edge in «Vistar» rats. The morphological research was conducted 30, 90 and 180 days after the experimental biomaterial transplantаtion into the bone defect. They showed a gradual replacement of biomaterial in compliance with the patterns of reparative regeneration. Originally, dense well-shaped fibrous connective tissue was formed in the transplant. The osteogenesis areas in the regeneration zone were revealed as early as in 30 days. The created biomaterial is optimum for regenerative reconstruction of the orbital walls thanks to its modelling, plasticity and osteogenous properties.
Key words: elastin biomaterial, orbital wall reconstruction, osteogenesis.
REFERENCES
- Oftal’mokhirurgiya s ispol’zovaniem polimerov, pod red. V.V. Volkova. Izd. 2-e, pererab. i dopoln. [Ophthalmosurgery using polymers. Ed. by V.V. Volkova. Ed. 2nd, Revised and complementary]. Saint Petersburg: Gippokrat, 2009. 568 p.
- Muldasheva I.E. Khirurgicheskoe lechenie posttravmaticheskikh gipoftal’ma i enoftal’ma s primeneniem biomaterialov Alloplant: avtoref. dis. … kand. med. nauk [Surgical treatment of post-traumatic enophthalmos and gipoftalma using biomaterials biomaterials. Synopsis of dis. PhD med. sciences]. Chelyabinsk, 2007. 18 p.
- Sel’skiy N.E. Ustranenie defektov i deformatsiy litsa kombinirovannymi allotransplantatami serii “Alloplant”: avtoref. dis. … d-ra med. nauk [Elimination of defects and deformations combined entity allografts series «biomaterials». Synopsis of dis. Dr med. sciences]. Saint Petersburg, 2000. 45 p.
- Galimova V.U., Muldasheva I.E., Sultanov R.Z. Opyt ispol’zovaniya biomateriala Alloplant v khirurgicheskom lechenii posttravmaticheskogo gipoftal’ma i enoftal’ma [Experience in the use of biomaterial biomaterials in surgical treatment of post-traumatic enophthalmos and gipoftalma]. VIII s»ezd oftal’mologov Rossii. Moscow, 2005. P. 639.
- Regenerativnaya meditsina. Biomaterialy Alloplant v oftal’mokhirurgii, pod obshch. red. E.R. Muldasheva [Regenerative medicine. Biomaterials Alloplant in ophthalmic surgery. Ed. by E.R. Muldashev]. Ufa: GUP “Bashkortostan”, 2014. 432 p.
- Muldashev E.R., Nigmatullin R.T., Galimova V.U. et al. Ksenogennyy biomaterial dlya regenerativnoy khirurgii: patent no. 2440148, prioritet 21.12.2009, opublik. 20.01.2012 [The heterologous biomaterial for regenerative surgery: patent №2440148, priority 21.12.2009, publish. 20.01.2012], byul. no. 2.
- Mikroskopicheskaya tekhnika. Rukovodstvo dlya vrachey i laborantov, pod red. D.S. Sarkisova i Yu.L. Petrova [The microscopic technique. Guidelines for doctors and laboratory technicians. Ed. by D.S. Sarkisov and J.L. Petrova]. Moscow: Meditsina, 1996. 544 p.
- Omel’yanenko N.P., Slutskiy L.I. Soedinitel’naya tkan’ (gistofiziologiya i biokhimiya). V 2 t. T. II [Connective tissue (histophysiology and biochemistry). In 2 volumes, Volume II]. Moscow: Izdatel’stvo “Izvestiya”, 2010. 600 p.