A.R. КLYUCHAROVA¹, S.А. АRKHIPOVA²

¹Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

²Kazan State Medical University, 49 Butlerov Str., Kazan, Russian Federation, 420012

Klyucharova A.R. ― Cand. Med. Sc., allergologist and immunologist, Assistant of the Department of Clinical Immunology and Allergology, tel. +7-917-282-44-14, e-mail: aliluia@yandex.ru

Arkhipova S.A. ― student, tel. +7-950-310-46-43, e-mail: sophia.sun@rambler.ru

This article provides information about the structural features of the brain lymphatic system. The main functions of T-lymphocytes, macrophages and dendritic cells оf meningeal system are named. The influence of cytokines, produced by cells of the immune system, on the work of the brain, as well as their possible impact on the formation of human cognitive disorders and depression, is described. The results of efficient therapy of depressive disorders by antibodies to TNF-a are given. The study of the functions of the brain lymphatic system allows us to find new mechanisms of the pathogenesis of a number of neurodegenerative diseases.

Key words: brain, lymphatic system, T-lymphocytes, cytokines.

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