M.A. KUNST¹, S.P. YAKUPOVA¹, O.D. ZINKEVICH², R.Z. ABDRAKIPOV³, M.A. AFANASYEVA³, E.V. SUKHORUKOVA³

¹Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

²Kazan State Medical Academy, 11 Butlerov St., Kazan, Russian Federation, 420012

³Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

Kunst M.A. — postgraduate student of Hospital Therapy Department, tel. (843) 298-37-70, kunstma@mail.ru¹

Yakupova S.P. — PhD (Medicine), Associate Professor of the Department of Hospital Therapy, tel. +7-917-869-30-18, e-mail: jakupova@kgmu.kcn.ru¹

Zinkevich O.D. — PhD (Biology), Deputy Head of the Central Research Laboratory, tel. +7-927-407-64-54, e-mail: zinkevich-oleg@mail.ru²

Abdrakipov R.Z. — Head of the Rheumatology Department, tel. +7-965-607-97-70 e-mail: hosptherapy@mail.ru³

Afanasieva M.A. — rheumatologist, tel. +7-917-273-12-94, e-mail: afmaria2108@mail.ru³

Sukhorukova E.V. — rheumatologist, tel. +7-917-270-85-24, e-mail: s_elena1407@mail.ru³ 

It is known that microbial infection plays a trigger role in a number of rheumatic diseases. There are findings about the role of urinary tract asymptomatic infection caused by Proteus in RA development, aa well as the role of subclinical bowel infections caused by Klebsiella in ankylosing spondylitis and Crohn’s disease. Molecular mimicry is considered the basic mechanism of these diseases development. Nowadays there are non-invasive methods of intestinal permeability assessment (нет в русском варианте — ЕН).

Key words: rheumatoid arthritis, intestinal permeability, bacterial mimicry.

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