PAVEL TOKAREV², ALEXYSHULAEV ², LUDMILAPLAKSINA ¹, DAMIR MARAPOV²

¹ Children Republic Clinical Hospital, Health Care Ministry of the Tatarstan Republic, Kazan, Russia (4200100, Kazan, Orenburgsky tract str., 140), e-mail: milaplax76@yandex.ru, facesurg@yandex.ru

2 Kazan State Medical University, Health Care Ministry of the Russian Federation , Kazan, Russia (Kazan,Butlerov str., 49) damirov@list.ru

Pavel Tokarev – doctor fhighest category, maxillofacialsurgeon, the head of maxillofacialsurgery department of Children Republic Clinical Hospital. Russia (4200100, Kazan, Orenburgsky tract str., 140), e-mail: facesurg@yandex.ru +7(843)237-54-00

Alexy Shulaev – Doctor of medicine, professor of Healthcare management department of carierdevelopment and professional retraining faculty of Kazan State Medical University. Kazan, Russia (Kazan, Butlerov str., 49) +7(843)269-92-29

Ludmila Plaksina – Ph.D. of medicine, pediatrician, the head of Medical –Social Care of Adolescents of Children Republic Clinical Hospital, Tatarstan Republic. Russia (4200100, Kazan, Orenburgsky tract str., 140), e-mail: milaplax76@yandex.ru +7(843)267-89-52

Damir Marapov-The assistant of Public health and health care organization with medical informatics course department of Kazan State Medical University. Kazan, Russia (Kazan, Butlerov str., 49) +7(843)238-73-79

The selective data of primary medical data sheets (delivery histories patient cards, case histories). This received numerical material was subjected to statistic processing with relative values calculation (intensive and extensive coefficient). Because of sample formation error probability, the error of frequency relative value was calculated at its 95% confidence interval of its true value. Labium and palate clefts have particular meaning in the large group of congenital failure of development as for severity of clinical appearance, anatomical and functional abnormalities which become stronger with child’s growth; and also by frequency expansion. They are at the 4-7 location among all types of congenital failure of development. The analysis of a search received data shows, that there are significant variation of congenital leaps and palate clefts frequency though out Tatarstan Republic territory during the research period. That index range varied from minimal value 0,8‰ (2003 year) to maximal value 4,0‰ (2011 year). The medium level during of all search period was 2,2 per 1000 newborn.

Key words: labium and palate cleft, genetic syndromes associated with maxillofacial region abnormalities, congenital maxillofacial region failure of development at children.

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