The Local Use of Infliximab in Pyoderma Gangrenosum
E.Yu. CHASHKOVA1, L.R. SHEDOEVA1,2, L.G. CHKHENKELI2, V.E. PAK2
1Research Centre of Reparative and Restorative Surgery, East Siberian Research Centre, Academy of Medical Science, Borcov Revolucii St. 1, Irkutsk, Russian Federation 664003
2Irkutsk State Medical University, Krasnogo Vosstaniya St. 1, Irkutsk, Russian Federation 664003
Chashkova Elena — PhD, surgeon-coloproctologist, Head of Laboratory of Reconstructive and Restorative Surgery, tel. +7-902-515-54-16, e-mail:eyuch@rambler.ru1
Shedoeva Lyudmila — graduate student, department of hospital surgery with the course of neurosurgery, tel. +7-924-609-12-89, e-mail: cristal608@yandex.ru1,2
Chkhenkeli Levan — graduate student, department of hospital surgery with the course of neurosurgery, tel. +7-950-102-06-93, e-mail: levan.chkhenkeli@rambler.ru2
Pak Vladislav — PhD, associate professor, department of hospital reconstructive surgery with a course neyrohirgii, Head of department of coloproctology, tel. +7-902-516-78-51, e-mail: pak_ve@iokb.ru2
The article presents the result of the treatment of a patient with Crohn’s disease and severe widespread pyoderma gangrenosum. The patient had been treated unsuccessfully longer than for two years by different specialists. The patient underwent the basic therapy and sigmoidostomy. The local injections of TNF-α blockers were performed. The affected area was completely healed.
Key words: Crohn’s disease,pyoderma gangrenosum, Infliximab.
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