I.F. AKHTYAMOV^1,2, P.S. ANDREEV², E.B. GATINA¹, E.I.-O. ALIEV¹

¹Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

²Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Tract, Kazan, Russian Federation, 420064

Akhtyamov I.F. — D. Med. Sc., Professor, Head of the Department of Traumatology, Orthopedics and Surgery of Extreme States, tel. + 7-905-315-01-50, e-mail: yalta60@mail.ru

Andreev P.S. — Cand. Med. Sc., Head of Traumatologic-Orthopedic (children’s) Department, tel. (843) 296-31-40, e-mail: rkb_nauka@rambler.ru

Gatina E.B. — Cand. Med. Sc., Competitor of the Department of Traumatology, Orthopedics and Surgery of Extreme States, tel. +7-903-330-799-50, е-mail: 2960091@mail.ru

Aliev E.I.-O. — Competitor of the Department of Traumatology, Orthopedics and Surgery of Extreme States, e-mail: alelil@mail.ru

Objective. The initial assessment of general and local reaction of the patient’s organism to osteosynthesis of implants with a new nanotechnology coating, as well as a possible inverse impact of organism tissues on the condition of bone fragments’ fixators. Materials and methods. Within the frameworks of a nanotechnological development programme and a tendency to import substitution, a new coating of implants for traumatology and orthopedics has been created and approved. After preclinical studies had been completed and permission for carrying out clinical stage testing had been received, the first 10 implantations were performed in children aged 3-5 years in the surgical treatment of congenital hip dislocation on the base of Traumatology and Orthopedics Clinic at the Kazan Medical University. Osteosynthesis of the ileum bone fragments was performed in six cases and osteosynthesis of proximal femur was performed in four cases under appropriate corrective osteotomies.Discussion of the results. The need for appliance of such fixators is stipulated by the large percentage of complications in the form of rejection of common fixators by the patient’s organism with the development of the so-called «metallosis» effect and subsequent infection in the area of ​​its installation. In all cases the outcome was positive. The authors managed to achieve complete fusion of fragments of the femoral and iliac bone with no symptoms of allergic or any other pathological reactions to the implant.

Key words: implants, coatings, an allergic reaction.

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