L.B. POSTNIKOVA, I.A. DOROVSKOY, V.A. KOSTROV

Municipal Hospital №28, 7 Chaadaeva Str., Nizhny Novgorod, Russian Federation, 603040

Postnikova L.B. ― D. Med. Sc., Associate Professor, Head of «Municipal Advisory Pulmonology Center», tel. (831) 276-84-12, e-mail: plbreаth@mail.ru

Dorovskoy I.A. ― physician, tel. (831) 276-84-12, e-mail: fiatlux2008@rambler.ru

Kostrov V.A. ― Cand. Med. Sc., Associate Professor, consultant-pulmonologist, tel. (831) 276-84-12, e-mail: vlakostr@yandex.ru 

The article presents differences of cardiopulmonary exercise testing (CPET) parameters in healthy smoking and non-smoking young men. We used the complex Quark CPET «COSMED» (Italy) and the modified Bruce Protocol to determine the tolerance to physical activity. We found a decreased tolerance to physical activity in healthy young smokers, which was confirmed by the early onset of anaerobic metabolism threshold, the decrease of peak time (t Peak) of the load performance, the reduced maximum oxygen consumption (IPC) and maximum aerobic performance (MET Peak). The increase of respiratory reserve (BR˃35%), low increase of heart rate (HR) and a decrease in oxygen pulse (VO2/HR˂20%) at the peak load in smokers show a decline of stroke volume and the role of hemodynamic mechanisms in limiting physical performance on the background of smoking. On the other hand, we registered a decrease in the maximum tidal volume (VT Peak) and maximum minute ventilation (VE Peak) at the peak stress in smoking subjects, which may indicate an underlying change in lung function. Thus, the revealed changes of the CPET parameters in smoking healthy young men demonstrate the development of early preclinical disorders of the cardiovascular and respiratory systems.

Key words: healthy young men, cardiopulmonary exercise testing, gas analysis, maximum consumption of oxygen.

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