A.R. SADYKOVA, A.R. SHAMKINA, R.I.GIZYATULLOVA

Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation 420012

Sadykova A.R. —Cand. Med. Sc., Associate Professor of the Department of Propedeutics to Internal Diseases, tel. +7-960-032-55-49, e-mail: aidasad@mail.ru

Shamkina A.R.— Cand. Med. Sc., AssistantLecturer of the Department of Propedeutics to Internal Diseases, tel. +7-904-665-28-83, e-mail: schamkina.aigul@yandex.ru

Gizyatullova R.I. — postgraduate student of the Department of Introduction to Internal Diseases, tel. +7-903-34-07-808, e-mail: rimma.giz_doc@mail.ru

The article represents the results of total cardiovascular risk evaluation in the nearest 10 years in hypertensive menopausal women in dependence on the inсidence of inappropriately high (IH) mass of left ventricular myocardium (LVM). 107 women — citizens of Kazan-city aged 42-59 – were examined. A survey included questionnaire, physical examination, biochemical blood test, ECG, and echocardiography. The disproportion coefficient (DC) was calculated by the ratio of actual LV mass to proper LV mass. It is reported that severely IH LVM in hypertensive menopausal women is associated with significantly higher (р<0.05 according to exact Fisher method) incidence of target organs damage (TOD) and with significantly higher (р<0,05 according to U criterion) average values of TOD sum, and total cardiovascular risk level. According to multiple regression results the DC is a significant (р<0.05) predictor of cardiovascular risk elevation in menopausal women.

Key words: inappropriately high mass of left ventricular myocardium, arterial hypertension, risk factors, target organs damage, total cardiovascular risk, menopausal women.

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