M.V. FROLOVA, V.I. RUZOV, R.R. KHAYRULLIN, M.A. MELNIKOVA, N.A. SLOBODNYUK

Ulyanovsk State University, Ulyanovsk

 Contact details:

Frolova M.V. — Assistant Lecturer of the Department of Faculty Therapy

Address: 42 Tolstoy St., Ulyanovsk, Russian Federation, 432970, e-mail: orangetopinambur@rambler.ru

The article is devoted to the study of the diagnostic informative value of serum cardiac markers (troponin I, caspase-8, amphiphysin-2) in patients with impaired carbohydrate metabolism after myocardial infarction. The study conducted on the 10^th day of the post-infarction period showed no relationship between the types of myocardial infarction and the severity of carbohydrate metabolism disorders. The study revealed an increase in amphiphysin-2 in patients of the study group compared with the control group, while the sensitivity and specificity of amphiphysin-2 in patients with Q-MI and non-Q MI were 97.8 and 13.0%, respectively. Elevated levels of amphiphysin-2 were accompanied by a simultaneous increase in serum levels of caspase-8 in the group of patients with myocardial infarction.

Key words: myocardial infarction, troponin I, caspase-8, amphiphysin-2, carbohydrate metabolism disorder.

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