L.T. BAYAZITOVA¹, O.F. TYUPKINA¹, T.A. CHAZOVA¹, Yu.A. TYURIN¹, I.D. RESHETNIKOVA¹, E.V. LUCHKINA² , S.B. MOSIKHIN³

¹Kazan Research Institute of Epidemiology and Microbiology of the Russian Agency for Consumer Supervision, 67 Bolshaya Krasnaya Str., Kazan, Russian Federation, 420015

²Children’s Republican Clinical Hospital of the Republic of Tatarstan Ministry of Healthcare, 140 Orenburgskiy Trakt, Kazan, Russian Federation, 420138

³Kazan State Medical Academy, 36 Butlerov Str., Kazan, Russian Federation, 420012

Bayazitova L.T. ― Cand. Med. Sc., Head of Scientific Research Laboratory of Microbiology, tel. (843) 236-67-91, e-mail: bajalt@mail.ru

Tyupkina O.F. ― Senior Researcher of Scientific Research Laboratory of Microbiology, tel. (843) 236-67-91, e-mail: ant11@mail.ru

Chazova T.A. ― Junior Researcher of Scientific Research Laboratory of Microbiology, tel. (843) 236-67-91, e-mail: kazkon@yandex.ru

Tyurin Yu.A. ― Cand. Med. Sc., Head of Scientific Research Laboratory of Immunology and Allergens Development, tel. (843) 236-67-91, e-mail: immunolab@mail.ru

Reshetnikova I.D. ― Cand. Med. Sc., Deputy Director, tel. (843) 236-67-81, e-mail: reshira@mail.ru

Luchkina E.V. ― Head of ENT Department, tel. +7-903-314-89-50, e-mail: luchkina_elena@inbox.ru

Mosikhin S.B. ― D. Med. Sc., Professor of Otorhinolaryngology Department, tel. +7-917-288-01-96, e-mail: serbor_ent8@mail.ru

The research is devoted to sensitivity profile to antimicrobiological medicines of Streptococcus pneumoniae clinical isolates found in nasal passages and back of the throat of pre-school children within the period 2009-2015. β-lactams are the most active antimicrobial agents against S.pneumoniae. Macrolides (azytromicin, clarytromicin) and cefalosporinous antibiotics III (cefixime, ceftriacson) also showd high activity against S. pneumoniae. The level of sensitivity to ciprofloxacin was reduced. A considerable regional variability of data concerning resistance strains in the population, especially among pre-school children, demands constant monitoring of the level of antibiotics sensitivity of Streptococcus pneumoniae in the city of Kazan.

Key words: clinical isolate, Streptococcus pneumonia, antimicrobial medicines.

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