P.I. NALYOTOVA¹, A.V. NALYOTOV², JA.A. SOCKAJA³, A.I. KHAVKIN^{4, 5}

 ¹Central City Clinical Hospital No. 1, Donetsk

²М. Gorky Donetsk State Medical University, Donetsk

³Lugansk State Medical University named after St. Luke, Lugansk

⁴Research Clinical Institute of Childhood, Moscow

⁵Belgorod National Research University, Belgorod

Contact details:

Nalyotov A.V. — MD, Professor, Head of the Department of Pediatrics No. 2

Address: 16 prospekt Ilyicha, 283003 Donetsk, Donetsk People’s Republic, Russian Federation, tel.: +7-960-467-52-98, e-mail: nalyotov-a@mail.ru

 In the recent years, the role of vitamin D in maintaining human health has been actively studied. Given the bactericidal, immunomodulatory, and anti-inflammatory effects of vitamin D, it is important to study the role of low vitamin D availability on the pathogenesis of intestinal diseases. The article analyzes modern literature sources devoted to the study of vitamin D provision in patients suffering from irritable bowel syndrome and the effectiveness of cholecalciferol intake for the disorder clinical symptoms. We found that among patients with irritable bowel syndrome, a decrease in vitamin D supply is frequent. In turn, studies evaluating the effectiveness of additional cholecalciferol supplementation in reducing the disorder symptoms show ambiguous results. Larger-scale and well-planned studies are needed to substantiate the therapeutic use of cholecalciferol in irritable bowel syndrome.

Key words: vitamin D, sufficiency, calcidiol, irritable bowel syndrome.

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