A.YU. LAZAREVA^{1, 2}, I.B. FATKULLINA^{1, 3}, E.A. SAGATDINOVA², T.KH. DALAEVA³

 ¹Bashkir State Medical University, Ufa

²Republican Clinical Hospital named after G.G. Kuvatov, Ufa

³Republican Clinical Perineal Center, Ufa

 Contact details:

Lazareva A.Yu. — postgraduate student of the Department of Obstetrics and Gynecology, obstetrician-gynecologist

Address: 3 Lenin St., 450008 Ufa, Russian Federation, tel.: 7-987-583-86-62, e-mail: lazarevaayu@mail.ru

 Premature detachment of a normally located placenta is an extremely severe complication of pregnancy, which is characterized by suddenness and peracute development, and the consequences of this condition can sometimes be irreparable. Placental abruption is one of the major obstetric syndromes, along with preeclampsia and fetal growth retardation, the pathogenesis of which is based on the so-called ischemic placental disease. Placentation disorders are associated with endothelial dysfunction, and insulin resistance is a morphological substrate of this pathology, along with other predictors. It is important to note that impaired glucose tolerance is the scourge of our time, so this topic is especially relevant.

The purpose — to evaluate insulin resistance as a predictor of premature detachment of the placenta.

Material and methods. 87 women were examined, who were divided into two groups: the main group with a history of placental abruption, and the control group without such history. The respondents were examined for insulin resistance using the HOMA-IR index.

Results. Insulin resistance markers were detected in patients with a history of placental abruption.

Conclusion. Insulin resistance can be considered as one of the predictors of premature detachment of the placenta.

Key words: placental abruption, pregnancy, insulin resistance, predictor.

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