M.A. MAKAROV, V.N. OSLOPOV, D.S. KOROTKOV, K.V. PAVLOVA

Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation 420012

Makarov M.A. — Cand. Med. Sc., Assistant Professor of the Department of Propaedeutics of Internal Diseases, tel. +7-917-292-22-41, e-mail: kpvbol@yandex.ru

Oslopov V.N. — D. Med. Sc., Professor, Head of the Department of Propaedeutics of Internal Diseases, tel. +7-905-316-25-35, e-mail: kpvbol@yandex.ru

Korotkov D. S. — student, tel. +7-919-648-05-13, e-mail: dimkakorotkov93@rambler.ru

Pavlova K. V. — student, tel. +7-953-483-24-53, e-mail: karina.pavlova@myrambler.ru

The article provides an overview of randomized studies of comorbidity of arterial hypertension and various forms of cancer pathology, possible risk of cancer and high blood pressure in the activity of certain genes: C-108T polymorphism of PON1 gene, C677T polymorphism of MTHFR gene, 308 AA/GA polymorphism of TNF-alpha gene, Xbai polymorphism of apoB gene. This study found that polymorphisms of genes can be involved in occurrence of both arterial hypertension and development of cancers.

Key words: arterial hypertension, oncopathology, breast cancer, the lung cancer, colorectal cancer, lung cancer, gall bladder cancer, C-108T polymorphism of PON1 gene, C677T polymorphism of MTHFR gene, 308 AA/GA polymorphism of TNF-alpha gene, Xbai polymorphism of apoB gene.

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