A.V. NALYOTOV, V.V. PUSHKARUK, S.I. VAKULENKO

1. Gorky Donetsk State Medical University, Donetsk

 Contact details:

Nalyotov A.V. — MD (medicine), Professor, Head of the Department of Pediatrics No. 2

Address: 16 prospekt Illyicha, Donetsk, Donetsk People’s Republic, Russian Federation, 283003, tel.: +7-960-467-52-98, e-mail: nalyotov-a@mail.ru

 The purpose to study the frequency of the small bowel bacterial overgrowth syndrome in children with varying degrees of obesity.

Materials and methods. 168 school-age children with constitutionally exogenous obesity were examined: 66 patients with grade I obesity (subgroup 1), 62 children with grade II obesity (subgroup 2) and 40 patients with grade III obesity (subgroup 3). The control group consisted of 30 children with normal body weight. All children were diagnosed with the small bowel bacterial overgrowth using a hydrogen breath test with lactulose loading.

Results. The small bowel bacterial overgrowth was found in 122 (72.6%) obese children, which was statistically significantly (p < 0.001) higher relative to the control group — 6 (15.0%) children. The frequency of the small intestinal bowel overgrowth in children increased with an increase in the obesity degree: in subgroup 1 — 41 (60.3%), in subgroup 2 — 48 (77.4%), in subgroup 3 — 33 (82.5%) patients.

Conclusions. For children with constitutionally exogenous obesity, the development of the small bowel bacterial overgrowth is characteristic. At the same time, we established an increase in the frequency of microbial intestinal imbalance in children with an increase in the obesity degree.

Key words: obesity, small bowel bacterial overgrowth, children.

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