D.I. ABDULGANIEVA¹, A.Kh. ODINTSOVA², D.D. MUKHAMETOVA¹, E.S. BODRYAGINA¹, A.Kh. RAMAZANOVA², N.A. CHEREMINA², T.Yu. AFANASIEVA¹ 

¹Kazan State Medical University, 49 Butlerova St., Kazan, Russian Federation420012

²Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064 

Abdulganieva D.I. — D. Med. Sc., Head of the Department of Hospital Therapy, tel. +7-987-296-27-68, e-mail: diana_s@mail.ru¹

Odintsova A.Kh. — PhD (Medicine), Head of the Department of Gastroenterology, tel. +7-987-290-53-44, e-mail: odincovaa@yandex.ru²

Mukhametova D.D. — postgraduate student of the Department of Hospital Therapy, tel. +7-904-763-40-11, e-mail: muhdilyara@gmail.com¹

Bodryagina E.S. — postgraduate student of the Department of Hospital Therapy, tel. +7-917-395-34-55, e-mail: snezenka@rambler.ru¹

Ramazanova A.Kh. — physician of the Department of Gastroenterology, tel. +7-927-404-74-40, e-mail: alsuramazan@mail.ru²

Cheremina N.A. — physician of the Department of Gastroenterology, tel. +7-917-269-69-08, e-mail: doctornat@mail.ru²

Afanasieva T.Yu. — intern of the Department of Hospital Therapy, tel. +7-937-526-29-41, e-mail: tyafanaseva@gmail.com¹

The article presents the results of the long-term observation of patients with Crohn’s disease, the data of patients with Crohn’s disease register are analyzed, the treatment practice from 2006 to 2013 is compared. The regional features of a course of Crohn’s disease had been determined. The changing in treatment tactics of these patients within 8 years is analyzed.

Key words: Crohn’s disease, inflammatory bowel disease, immunosuppressive therapy, biological therapy.

REFERENCES

1. Ivashkin V.T., Shelygin Yu.A., Abdulganieva D.I. et al. Draft clinical guidelines for the diagnosis and treatment of adult patients with Crohn’s disease. Koloproktologiya, 2013, no. 3 (45), pp. 22-38 (in Russ.).

2. Burisch J. Crohn’s disease and ulcerative colitis. Occurrence, course and prognosis during the first year of disease in a European population-based inception cohort. Dan. Med. J., 2014, no. 61 (1), B.4778.

3. Safarpour A.R., Hosseini S.V., Mehraban D. Epidemiology of Inflammatory Bowel Diseases in Iran and Asia. Iran J. Med. Sci., 2013, no. 38 (2), r. 140-149.

4. Abdulganieva D.I., Odintsova A.Kh., Bodryagina E.S. et al. Regional features of chronic inflammatory bowel diseases. Prakticheskaya meditsina, 2010, no. 3 (42), pp. 69-71 (in Russ.).

5. Soon I.S., Molodecky N.A., Rabi D.M. et al. The relationship between urban environment and the inflammatory bowel diseases: a systematic review and meta-analysis. BMC Gastroenterol., 2012, no. 24, r. 1-14.