А.Т. FAIZUTDINOVA^1, 2, E.I. BOGDANOV^1, 2, T.G. SAKOVETS^1, 2, M.M. KHABIBRAKHMANOVA³, M.A. KHAIRULLOV¹, S.V. FILIMONCHEVA¹, V.I. ANISIMOV¹, A.G. AKHUNOVA¹, R.I. DAVLETSHINA¹, R.I. RAKHIMULLINA¹, D.F. SEMUSHINA¹, KH.I. MAMEDOV¹, A.R. AKHMETOVA², Z.I. SAFINA²

 ¹Republic Clinical Hospital, Kazan

²Kazan State Medical University, Kazan

³Gymnasium No. 21, Kazan

 Contact details:

Faizutdinova A.T. — PhD (Medicine), Associate Professor of the Department of Neurology, neurologist of Clinical Expert Department

Address: 138 Orenburgskiy trakt, Kazan, Russian Federation, 420064, tel.: +7-903-306-44-38, e-mail: aisluzab@mail.ru

 The clinical symptoms of Chiari malformation type 1 (CM1) are formed as a result of a combination of traction, compression, and occlusive processes in patients with a small volume of the posterior cranial fossa and dislocation of the cerebellar tonsils and are characterized by a wide variety combined with low specificity. This complicates the clinical diagnosis of this pathology, assessment of its severity and dynamics. Currently, the only clinical symptoms questionnaire designed specifically for patients with СM1 is the Chiari Symptom Profile (CSP), created by D.M. Muller and J.J. Oro and tested on an English-speaking cohort of adult patients. The Republic of Tatarstan is one of the regions of the Russian Federation with an increased incidence of СM1 and СM1-associated syringomyelia, which determines the relevance of studying the clinical symptoms of СM1 and searching for methods of early clinical diagnosis of this pathology.

The purpose of this work was to determine the prospects of using the CSP questionnaire in adult CM-patients with Chiari malformation in the Republic of Tatarstan. As a result of the standard procedure of translation, adaptation and approbation, versions of the questionnaire were created in the Russian and Tatar languages. Validation showed their reliability and discriminant validity.

Key words: Chiari malformation type 1, syringomyelia, Chiari malformation type 0, headache, ectopia of the cerebellar tonsils, questionnaire validation.

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