Prospects for using immunostimulating agents with nonspecific antiviral activity in the complex treatment of children with chronic adenoiditis
E.M. POKROVSKAYA1, 2, S.V. KHALIULLINA3, V.N. KRASNOZHEN1, 2, E.F. MANNANOVA1, 2
1Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan
2Kazan (Volga) Federal University, Kazan
3Kazan State Medical University, Kazan
Contact details:
Pokrovskaya Elena Mikhailovna – MD, otolaryngologist, Professor of the Department of Surgery, Obstetrics and Gynecology
Address: 36 Butlerov Str., 420012 Kazan, tel.: +7917-263-90-96, e-mail: epokrunia@inbox.ru
The article presents the results of studies on using inosine pranobex in children with pharyngeal tonsils hypertrophy of the 3rd degree after surgical intervention to prevent the development of pharyngeal tonsillitis relapses and compensatory hypertrophy of palatine tonsils in the postoperative period. 355 children aged 3 to 7 years old with a diagnosis of pharyngeal tonsil hypertrophy of the 3rd degree were examined. Laboratory methods of examination included qualitative studies to detect DNA of lymphotropic herpesviruses (EBV, CMV, HHV-6) in flushes from the nasopharyngeal mucosa. As a result of the conducted research, it was revealed that the inclusion of inosine pranobex in the complex treatment of children with chronic adenoiditis with verified herpesvirus infection is clinically effective and helps to reduce the risk of recurrence of pharyngeal tonsil hypertrophy and compensatory palatine tonsil hypertrophy.
Key words: adenoiditis, tonsil hypertrophy, herpesviruses, children.
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