G.P. Martynova¹, I.A. Solovyova¹, M.L. Menschikova², E.S. Erohina², A.B. Belkina², N.A. Bezrukih²

¹Krasnoyarsk State Medical University named after prof. V.F. Voyno-Yasenetsky, 1 Partizan Zheleznyak Str., Krasnoyarsk, Russian Federation, 660022

²Krasnoyarsk Interregional Children’s Clinical Hospital №1, 149 Lenin Str., Krasnoyarsk, Russian Federation, 660016

 Martynova G.P. ― D. Med. Sc., Professor, Head of Department of Pediatric Infectious Diseases with the course Postgraduate Education, tel. (391) 224-33-05, e-mail: doc-martynova@yandex.ru

Solovieva I.A. ― Cand. Med. Sc., Assistant of the Department of Pediatric Infectious Diseases with the course Postgraduate Education, tel. +7-913-556-55-33, e-mail: iasolov@mail.ru

Menshchikova M.L. ― doctor of infectious diseases of the IV infectious Department of the hospital for 160 beds, tel. (391) 224-33-05, e-mail: muzgdkb1@mail.ru

Erokhina E.S. ― doctor of infectious diseases of the IV infectious Department of the hospital for 160 beds, tel. (391) 224-33-05, e-mail: muzgdkb1@mail.ru

Belkina A.B. ― deputy chief physician on medical work, tel. (391) 224-33-05, e-mail: muzgdkb1@mail.ru

Bezrukikh N.A. ― doctor of infectious diseases of the IV infectious Department of the hospital for 160 beds, tel. (391) 224-33-05, e-mail: muzgdkb1@mail.ru

Objective ― to study the clinical and epidemiological features of RVI in children 1-3 years of life, and to evaluate the effectiveness of the drug «Bac-Set baby» in the complex treatment of the disease.

Material and methods. The study involved 74 patients aged 1-3 years. In order to evaluate the effectiveness of therapy, the patients were divided into two groups: primary (36) and control group (38 people). The main group consisted of 36 children, who from the first day of hospital treatment, along with pathogenetic therapy enterosorbents, received multi- probiotic «Bac-Set baby».

Results and discussion. The duration of intoxication syndrome in the study group averaged 3.4 [2,7-3,8] of the day, marked by significant shorter duration of febrile period (3.6 [3.7-4.0] days), vomiting (2.5 [2,4-3,9] days) and diarrhea syndrome, which amounted to 4.6 [4,3-6,7] days in the study group, compared to 5.1 [5,0-7,9] days ― in the comparison group.

Conclusion. It was found that the positive effect of the application of a multi-probiotic «Bac-Set baby» is aimed at the reduction or complete disappearance of symptoms of intoxication, reducing stool frequency, improve his character and consistency, cupping vomiting, and as a result, relief ecsicosis. In all cases we observed good tolerability, the absence of adverse events.

Key words: children, rotavirus infection, therapy.