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  • Pregnancy management in a liver transplant patient

    Редактор | 2026, Clinical case, Practical medicine part 24 №2. 2026 | 18 апреля, 2026

    N.A. NIGMATULINA1, 2, K.A. CHIKMAREVA1

     1Kazan State Medical University, Kazan

    2Republic Clinical Hospital, Kazan

    Contact details:

    Chikmareva K.A. — resident doctor, Department of Obstetrics and Gynecology named after V.S. Gruzdev

    Address: 49 Butlerova St., Kazan 420012, Russian Federation, tel.: +7 (843) 236-06-23, e-mail: k-chikmareva@yandex.ru

    Pregnancy after liver transplantation poses a high risk for the patient and fetus due to the medications taken and the associated medical history. The article describes a case of a successful second pregnancy and childbirth in a 42-year-old patient with a liver transplant following liver cirrhosis resulting from AIH overlap syndrome combined with primary biliary cirrhosis. The pregnancy was managed with hormonal therapy and Tacrolimus, with comprehensive daily laboratory monitoring. A planned cesarean section was performed at 37 weeks, resulting in the birth of a healthy baby girl weighing 2650 grams, 49 cm in length, 8-9 Apgar score. The pregnancy was with threatening interruption and moderate preeclampsia managed by antihypertensive medications.

    Conclusions. This clinical case demonstrates the possibility of a favorable outcome in a repeat pregnancy and birth, despite the high risk to the patient and fetus, provided that the team provides dynamic clinical monitoring.

    Key words: pregnancy, transplanted liver, liver transplantation

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    Метки: 2026, K.A. CHIKMAREVA, liver transplantation, N.A. NIGMATULINA, Practical medicine part 24 №2. 2026, pregnancy, transplanted liver

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