A.KH. BULATOVA^1, 2, V.G. SHAKIROVA¹, A.R. SAUBANOVA¹, Z.L. KHAMIDULLINA²

 ¹Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan

²Republic Clinical Infectious Hospital named after Prof. A.F. Agafonov, Kazan

 Contact details:

Bulatova A.Kh. — post-graduate student of the Department of Infectious Diseases

Address: 36 Butlerov St., Kazan, Russian Federation, 420012, tel.: +7-909-308-12-51, e-mail: Asiyakhaertynova@gmail.com

Among the natural-focal infections registered in the territory of the Republic of Tatarstan, the most common is hemorrhagic fever with renal syndrome (HFRS). In children, the clinical manifestations of HFRS may differ from the classical clinical picture characteristic for adults, with possible atypical course of the disease. Rare manifestations of HFRS in children include effusions in various areas of the body: the pleural cavity, pericardium, or pelvic cavity. The article presents a case of HFRS in a 13-year-old child who developed polyserositis manifesting as an effusion in the pleural cavity, pericardium, and pelvic cavity. Given the possible development of polyserositis in HFRS, an ultrasound of the pleural cavity, heart, abdominal and pelvic organs is suggested.

Key words: hemorrhagic fever, children, polyserositis.

REFERENCES

1. Savitskaya T.A., Ivanova A.V., Isaeva G.Sh. et al. Evaluation of the epidemiological situation of hemorrhagic fever with renal syndrome in the world and Russia, forecast for 2020. Problemy osobo opasnykh infektsiy, 2020, no. 2, pp. 62–70 (in Russ.).
2. https://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=17714
3. Kiseleva L.M., Gruzintseva Yu.P. Features of the clinical course of hantavirus infection in some regions of the Volga Federal District. Infektsionnye bolezni, 2010, vol. 8, appl. no. 1, Materialy ΙΙ Ezhegodnogo Kongressa po infektsionnym boleznyam, pp. 143–144 (in Russ.).
4. Morozov, V.G., Ishmukhametov A.A., Dzagurova T.K. et al. Clinical features of hemorrhagic fever with renal syndrome in Russia. Meditsinskiy sovet, 2017, no. 5, pp. 156–161 (in Russ.).
5. Roshchupkin V.I., Suzdal’tsev A.A. Gemorragicheskaya likhoradka s pochechnym sindromom [Hemorrhagic fever with renal syndrome]. Samara: Izd. Universiteta, 1995. 350 p.
6. Shakirova V.G., Gayfullina E.G., Khaertynova I.M. Hemorrhagic fever with renal syndrome: analysis of the epidemiological situation in the Republic of Tatarstan for the period 2003–2015. Dnevnik Kazanskoy meditsinskoy shkoly, 2017, no. 2 (16), pp. 21–24. (IF-0,147) (in Russ.).
7. Ivanova A.V., Popova N.V., Karnaukhov I.G., Chumachkova E.A. Hantavirus diseases: a review of the epidemiological situation and epidemiological risks in the regions of the world. Problemy osobo opasnykh infektsiy, 2021, no. 1, pp. 23–31 (in Russ.).
8. Huttunen N.P., Mäkelä S., Pokka T., Mustonen J., Uhari M., Systematic literature review of symptoms, signs and severity of serologically confirmed nephropathy epidemic in pediatric and adult patients. Scandinavian Journal of Infectious Diseases, 2011, vol. 43 (6-7), pp. 405–410.
9. Zhang L., Ma Qs., Zhang Y. et al. Analysis of misdiagnosed cases of hemorrhagic fever with renal syndrome in children: two cases and literature review. BMC Nephrology, 2019, vol. 20 (1), p. 383. DOI: 10.1186/s12882-019-1562-0
10. Ivanov D.O., Timchenko V.N., Pavlova E.B. et al. Hemorrhagic fever with renal syndrome in a young child. Zhurnal infektologii, 2020, no. 12 (5), pp. 152–158 (in Russ.).
11. Bahk YW., Kim CY., Radiologic manifestations of epidemic haemorrhagic fever with renal syndrome. The British Journal of Radiology, 1978, vol. 51 (611), pp. 847–850.
12. Linderholm M., Billstrom A., Settergren B., Tarnvik A., Pulmonary involvement in nephropathiaepidemica as demonstrated by computed tomography. Infection, 1992, vol. 20, rr. 263–266.
13. Park K.H., Kang Y.U., Kang S.-J., JungY.-S., Jang H.-C., Jung S.-I. Experience with Extra renal Manifestations of Hemorrhagic Fever with Renal Syndrome in a Tertiary Care Hospital in South Korea. American Journal of Tropical Medicine and Hygiene, 2011, vol. 84 (2), pp. 229–233.
14. Qiu F.Q., Li C.C., Zhou J.Y. Hemorrhagic fever with renal syndrome complicated with aortic dissection: A case report. World Journal of Clinical Cases, 2020, vol. 8, pp. 5795–5801.
15. Kim E.A., Lee K.S., Primack S.L., Yoon H.K., Byun H.S., Kim T.S. et al. Viral pneumonias in adults: radiographic and pathologic findings. Radiographics, 2002, vol. 22, pp. 137–149.
16. Losada I., Moreno Juan González; Roda N., Ventayol L., Borjas Y., Domínguez F.J., Fernández V., Victoria G.G., Mercedes; Payeras A. Polyserositis: a diagnostic challenge. Internal Medicine Journal, 2018, vol. 48 (8), pp. 982–987.
17. Mackow E., Gavrilovskaya I. Hantavirus regulation of endothelial cell functions. Thrombosis and Haemostasis, 2009, vol. 102 (6), pp. 1030–1041.