Physiological hemodilution during the second trimester of pregnancy and its role in perinatal outcomes
T.P. ZEPHIROVA1, I.Kh. SABIROV2, R.S. ZAMALEEVA1, M.E. ZHELEZOVA1
1Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012
2Republican Clinical Hospital №2, 1a Chekhov St., Kazan, Russian Federation, 420013
Zephirova T.P. ― D. Med. Sc., Professor of the Department of Obstetrics and Gynecology №1, tel. +7-987-290-45-99, e-mail: tzefirova@gmail.com
Sabirov I.Kh. ― obstetrician-gynecologist of the obstetrical department, tel. +7-917-916-17-00, e-mail: i.sabirov83@gmail.com
Zamaleeva R.S. ― D. Med. Sc., Professor of the Department of Obstetrics and Gynecology №1, tel. +7-919-621-67-51, e-mail: zamaleewa@rambler.ru
Zhelezova M.E. ― Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology №1, tel. +7-919-627-13-66, e-mail: gelezovam@gmail.com
The article presents current understanding of the flow properties of blood and the importance of gestational physiological hemodilution for optimal utero-placental blood flow. Data of pregnancy monitoring in women with elevated blood concentration are represented. It was found that pregnancy with haemoconcentration occurs with various complications, the most common of which is the fetal growth retardation. It happened to 40% of newborns. The study of blood viscosity showed that women with haemoconcentration had significant increase in value of this indicator at low shear rates. This fact indicates the possible problems of microcirculation and uteroplacental link.
Key words: pregnancy, hemodilution, blood viscosity, growth retardation.
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