А.Т. FAYZUTDINOVA^1,2, M.A. ZARIPOVA¹

¹Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

²Kazan State Medical University of the MH of RF, 49 Butlerov Str., Kazan, Russian Federation, 420012

 Fayzutdinova A.T. ― PhD (medicine), Associate Professor of the Department of Neurology and Rehabilitation, Neurologist of the Clinical and Expert Department, e-mail: aisluzab@mail.ru

Zaripova M.A. ― Neurologist of the Neurology Department for patients with cerebrovascular accident, e-mail: zaripova.m.a@mail.ru

 The bone phenotype of the posterior cranial fossa (PCF), which affects cerebrospinal fluid dynamics, can potentially affect cerebral circulation. The connection of clinical outcomes of ischemic strokes to transient ischemic attack with posterior cranial fossa phenotype parameters was analyzed. 152 patients and 40 control subjects were examined. Among patients with acute impairment of the cerebral circulation, in general, reduced linear or volume parameters of the posterior cranial fossa that are not associated with known anomalies of the craniovertebral transition or age-related changes, were detected in 48%. A similar index for strokes with a lethal outcome was 81%. Further investigations with the study of clinical-structural correlations will allow expanding the understanding of the role of the bone phenotype of posterior cranial fossa during cerebrovascular pathology.

Key words: ischemic stroke, transient ischemic attack, bone phenotype, posterior cranial fossa, outcomes of stroke.

(For citation: Fayzutdinova A.T., Zaripova M.A. Outcomes of ischemic strokes and transient ischemic attack: the role of bone phenotype of posterior cranial fossa. Practical Medicine. 2018)

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