YU.V. GARIFULLOVA, L.I. MALTSEVA, N.Z. YUSUPOVA, O.V. DANILOVA

 Kazan State Medical Academy — Branch Campus of the FSBEI FPE RMACPE MOH Russia, Kazan, Russia

Contact details:

Garifullova Yu.V. — PhD (medicine), Associate Professor of the Department of Obstetrics and Gynecology

Address: 36 Butlerov St., 420012 Kazan, Russian Federation, tel.: +7 (843) 236-46-41, е-mail: gamil.garifullov@yandex.ru

Changing lifestyle is one of the most effective methods of breast cancer primary prevention. Increased consumption of foods rich in iron, vitamin D, soy isoflavones, indole-3-carbinol and omega 3 fatty acids is a huge resource for reducing the risk of breast cancer in women, regardless of menopause status. The main anticarcinogenic mechanisms of these biologically active substances include modulation of proliferation, apoptosis, neoangiogenesis and epithelial-mesenchymal transition. Recent studies also demonstrated the possible influence of nutrient factors on the intestinal microbiome, which makes a significant contribution to changing the risk of oncopathology in women.

Key words: breast cancer, nutrients, epigenetics, isoflavones, vitamin D, omega-3 fatty acids, cruciferous vegetables.

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