Non-motor symptoms of Parkinson’s disease, their structure and influence on the quality of life of patients
E.A. RABADANOVA, M.A. GELPEY, Z.A.GONCHAROVA
Rostov State Medical University, 29 Nakhichevanskшy St., Rostov-on-Don, Russian Federation, 344022
Rabadanova E.A. — postgraduate student of the Department of Nervous Diseases and Neurosurgery, tel. +7-918-558-91-80, е-mail: a_a_b@bk.ru
Gelpey M.A. — ordinator of the Department of Nervous Diseases and Neurosurgery, tel. +7-951-507-09-07, е-mail: gelpey.margo@gmail.com
Goncharova Z.A. — D. Med. Sc., Professor of the Department of Nervous Diseases and Neurosurgery, tel. +7-928-100-34-44, е-mail: centrms@mail.ru
Parkinson’s disease (PD) includes motor and non-motor types of symptoms that have a considerable influence on quality of life and restrict everyday and social activity. The aim of the research was to study the availability, the frequency, the structure and the evidence of non-motor symptoms in different stages of PD to appreciate their influence on quality of patients’ life and correlation between duration of PD and basic motor characteristics of disease. The materials and the methods: we examined 54 patients with the diagnosis of Parkinson’s disease having used the Unified Parkinson’s Disease Rating Scale (UPDRS), the Montreal Cognitive Assessment (MоCA), the Beck Depression Inventory, the Non-Motor Symptoms Scale (NMSS) and the Non-motor symptoms Questionnaire (PD NMS). The results: non-motor symptoms are the obligatory signs in the structure of PD. We discovered the significant dependence of evidence of non-motor symptoms on the stage and the points of UPDRS. We can note the dependence of quality of life on the case, the stage of the disease, the evidence of depression and the patients’ age. This research showed that quality of patients’ life is more dependent on evidence of motor impairments than on non-motor types of symptoms. Conclusion: non-motor symptoms are the obligatory signs of Parkinson’s disease and have a considerable influence on quality of patients’ life.
Key words: Parkinson’s disease, non-motor symptoms, quality of life.
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