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  • New possibilities for early diagnosis of hilar cholangiocarcinoma using the TurboHawk catheter for directed biopsy

    Редактор | 2017, Original articles, Practical medicine 06 (17) Surgery | 21 сентября, 2017

    Yu.A. KOVALENKO, Yu.O. ZHARIKOV, S.A. TRIFONOV, D.V. KALININ, A.B. VARAVA, A.V. ZHAO

    A.V. Vishnevsky Institute of Surgery, 27 Bolshaya Serpukhovskaya Str., Moscow, Russian Federation, 117997

    Kovalenko Yu.A. – Cand. Med. Sc., Senior Researcher of the Department of Abdominal Surgery, Department of Surgical Hepatology and Pancreatology, tel. (499) 237-25-53, e-mail: kovalenkoya@rambler.ru

    Zharikov Yu.O. – postgraduate student of the Department of Abdominal Surgery, Department of Surgical Hepatology and Pancreatology, tel. +7-916-647-99-38, e-mail: dr_zharikov@mail.ru

    Trifonov S.A. – clinical intern, tel. +7-985-811-23-23, e-mail: dr_zharikov@mail.ru

    Kalinin D.V. – Cand. Med. Sc., Head of the Department of Pathological Anatomy with the laboratory of electronic microscopy, tel. (499) 237-25-53, e-mail: dmitry.v.kalinin@gmail.com

    Varava A.B. – Junior Researcher of the Department of Reontgen Surgical Diagnostics and Treatment Methods, tel. +7-916-318-49-43, e-mail: varava@ixv.ru

    Zhao A.V. – D. Med. Sc., Professor, Deputy Director on academic work, tel. (499) 237-25-53, e-mail: chzhao@ixv.ru

    Early diagnosis of hilar cholangiocarcinoma is still a challenge for modern medicine. We have studied the diagnostic results of hilar cholangiocarcinoma with the TurboHawk catheter for directed biopsy. In 2014-2016 20 patients of A.V. Vishnevsky Institute of Surgery with suspected hilar cholangiocarcinoma underwent biopsy of bile duct tumor with the TurboHawk device; 6 patients (30 %) were found positive for cholangiocarcinoma and underwent liver and bile duct resection with the formed hepaticojejunostomy. 9 patients (45 %) had unresectable tumor and underwent external-internal or external drainage of bile duct followed by chemioradial therapy. 5 (25 %) patients were found negative for cholangiocarcinoma and stayed under dynamic observation. The method sensitivity was 100 %, specificity — 89 %, and prognostic value — 92 %. Thus, the directed biopsy with the TurboHawk catheter is a high-precision method and allows to substantiate the hilar cholangiocarcinoma with 92 % reliability. However, the diagnossticaccuracy has to be proved by further research.

    Key words: hilar cholangiocarcinoma, percutaneous transhepatic cholangiostomy, intraductal biopsy, TurboHawk atherectomy catheter.

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    Метки: 2017, A.B. VARAVA, A.V. ZHAO, D.V. KALININ, hilar cholangiocarcinoma, intraductal biopsy, percutaneous transhepatic cholangiostomy, Practical medicine 06 (17) Surgery, S.A. TRIFONOV, TurboHawk atherectomy catheter, Yu.A. KOVALENKO, Yu.O. ZHARIKOV

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