E.Yu. PONOMARYOVA, Yu.G. SHVARTS

Razumovskiy Saratov State Medical University, 112 Bol’shaya Kazachya St., Saratov, Russian Federation 410012

Ponomaryova E.Yu. — Cand. Med. Sc., Associate Professor of Hospital Therapy Department of Therapy Faculty, tel. +7-917-214-16-75, email: ponomareva_elena1@mail.ru

Shvatrs Yu.G. — D. Med. Sc., Professor, Head of Hospital Therapy Department of Therapy Faculty, tel. +7-927-220-11-01, email shwartz58@yandex.ru

The work objective was to examine the incidence, clinical features, diagnostic difficulties, and outcomes of myocardial infarction (MI) in patients with infective endocarditis (IE). A retrospective analysis of hospitalized patients (n=262) with a significant native valve IE was fulfilled. MI was diagnosed in 14 patients (5.3%), more often — of anterior localization (11 patients), found only in males, with left-sided IE, mainly in the onset of the disease and caused a diagnostic error in 10 patients. We marked a great expression of hypertrophy and dilatation of the left ventricle, the magnitude of pulmonary hypertension, severe heart failure, more often the intracardiac destructions (perforation and detachment of folds) (p<0.05), and a two-fold increase in mortality in patients with MI in IE than in those without MI. (43% vs 19%, p<0.05). The possible mechanisms of myocardial infarction and diagnostic difficulties in IE were discussed in comparison with literature data.

Key words: infective endocarditis, myocardial infarction.

 

 

 

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