N.V. SKRIPCHENKO^1, 2, A.A. VILNITS^1, 2, M.K. BEKHTEREVA^1, 2, E.YU. SKRIPCHENKO^1, 2, A.I. KONEV^1, 2, K.V. MARKOVA¹, YU.E. KONSTANTINOVA¹

 ¹Pediatric Research and Clinical Center for Infectious Diseases, Saint Petersburg

²Saint Petersburg State Pediatric Medical University, Saint Petersburg

Contact details:

Skripchenko N.V. — MD, Professor, Honored Researcher of the Russian Federation, Deputy Director for Research, Head of the Department of Infectious Diseases

Address: 9 Professor Popov St., Saint Petersburg, Russian Federation, 197022, tel.: +7 (812) 234-10-38, e-mail: snv@niidi.ru

Multisystem inflammatory syndrome in children associated with SARS-CoV-2 (MIS-C), which has signs of Kawasaki disease, can occur under the guise of various diseases and is characterized by a variety of clinical symptoms, severe damage to organs and systems. The polymorphism of the clinical picture of the disease causes difficulties in making a diagnosis, requires an integrated approach in the diagnosis and treatment of such patients, as well as long-term dynamic monitoring by specialized doctors (neurologist, cardiologist, hematologist, etc.). The article presents two clinical cases of children with MIS-C. The patients were hospitalized with suspected neuroinfection (meningitis?), however, a correctly collected medical history and clinical and laboratory data that met the WHO criteria made it possible to make the diagnosis and conduct adequate complex therapy.

Key words: multisystem inflammatory syndrome in children associated with SARS-CoV-2, clinical case, neuroinfections, meningitis, COVID-19.

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