E.M. MIKHEEVA¹, N.I. PENKINA²

 ¹Republic Clinical Hospital, Izhevsk

²Izhevsk State Medical Academy, Izhevsk

Contact details:

Mikheeva E.M. — neonatologist of the Department of Pathology of Newborns and Premature Babies

Address: 57 Votkinskoye shosse, Izhevsk, Russian Federation, 426039, tel.: +7-906-819-92-56, e-mail: alena-sher@yandex.ru

Studying the morbidity of young children conceived with the help of assisted reproductive technologies (ART) is important for improving medical care.

The purpose — to study the morbidity of young children born with the use of assisted reproductive technologies.

Material and methods. A retrospective examination involved 82 young children born with the use of assisted reproductive technologies, including 35 full-term and 47 premature babies. The comparison group consisted of children of the first three years of life from spontaneous pregnancies, of which 45 were full-term and 31 premature babies.

Results. Respiratory diseases in full-term (p = 0.006) and premature (p = 0.032) babies conceived with the use of ART occupy a leading place in the structure of somatic pathology at an early age. The formation of resistance in young children conceived with the use of ART is influenced by: being born small to gestational age (p < 0.001), early start of artificial feeding (p < 0.001), anemia (p = 0.014), the presence of allergic diseases (p < 0.001), the lack of vaccination against Haemophilus influenzae infection (p < 0.001), non-rational use of antibiotic therapy (p = 0.001), smoking of one of the parents (p < 0.001). The factors that determine the formation of malformations in young children conceived with the use of ART are: the age of the mother (p = 0.019) and the father over 31 years (p = 0.017), the onset of pregnancy from two or more IVF attempts (p < 0.001), acute respiratory infections before 12 weeks of pregnancy (p < 0.001), chronic gynecological diseases of the mother (p = 0.023). The consequences of perinatal damage to the nervous system were diagnosed in the majority of full-term (p = 0.001) and premature (p < 0.001) babies conceived using ART.

Conclusions. In children of the first three years of life conceived with the help of assisted reproductive technologies, a high level of somatic and neurological pathology was revealed.

Key words: assisted reproductive technologies, young children, health, somatic pathology.

(For citation: Mikheeva E.M., Penkina N.I. Morbidity of young children born with the use of assisted reproductive technologies. Practical medicine. 2023. Vol. , № , P.)

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