S.V. SERGIYKO¹, S.A. LUKYANOV¹, S.E. TITOV^2-4, Yu.A. VERYASKINA²

¹South-Ural State Medical University, Chelyabinsk

²Institute for Molecular and Cell Biology of Siberian branch of the Russian Academy of Sciences, Novosibirsk

³Vektor-Best JSC, Novosibirsk

⁴Novosibirsk State University, Novosibirsk

  Contact details:

Lukyanov S.A. ― PhD (medicine), Assistant of the Department of General and Children’s Surgery

Address: 64 Vorovskiy Str., Chelyabinsk, Russian Federation, 454092, e-mail: 111lll@mail.ru

Fine-needle aspiration biopsy (FNA) of thyroid nodes under US-control with subsequent cytological examination is the main way to assess the risk of malignancy of these formations. At the same time, the diagnostic capabilities of cytological examination in follicular tumors and thyroid neoplasia have diagnostic limitations. «Uncertain» and tumor suspicious cytological findings are an argument for sending patients to unreasonable, in most cases, surgical treatment. The article deals with the diagnostic capabilities of the Russian genetic molecular classifier developed by IMCB of SB RAS for differential diagnosis of thyroid tumors in patients with cytological conclusion «follicular tumor» (Bethesda IV, 2017).

Key words: follicular thyroid tumor, thyroid cancer, molecular genetic testing.

(For citation: Sergiyko S.V., Lukyanov S.A., Titiv S.E., Veryaskina Yu.A. Molecular-genetic testing in differential diagnostics of node lesions in thyroid gland with cytological conclusion of «follicular tumor Bethesda IV». Practical medicine. 2019. Vol. 17, № 4, P. 149-152)

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