A.V. LARYUKOV^1,2, E.K. LARYUKOVA²

¹Tatarstan Cancer Center, 29 Sibirskiy Trakt, Kazan, Russian Federation, 420029

²Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

Laryukov A.V. ― Cand. Med. Sc., Head of the Radiology Departmrnt, Assistant Professor of the Department of Ultrasonic Diagnostics, Assistant of the Department of Oncology, Radiology and Palliative Medicine, tel. (843) 525-72-32, e-mail: larioukov@mail.ru

Laryukova E.K. ― Cand. Med. Sc., Associate Professor of Radiation Diagnosis, tel. +7-962-555-78-01, e-mail: elaryukova@icloud.com

Intended use of methods of radiation and nuclear diagnostic for detection of bone metastases in peripheral non-small cell lung cancer help to clarify the tumor stage and to choose adequate treatment strategy. The article presents the results of using a complex of modern methods of radiation and nuclear diagnostics (SPET/CT, PET/CT with fluorodeoxyglucose) in 71 patients with peripheral non-small cell lung cancer to detect bone metastases. The evaluation of the diagnostic capabilities of SPET/CT, PET/CT with fluorodeoxyglucose is presented.

Key words: single-photon emission tomography (SPET), positron emission tomography (PET), peripheral non-small cell lung cancer (PNSCLC), metastases, bones.

REFERENCES

1. Davydov M.I., Aksel’ E.M. The incidence of malignant tumors in Russia and CIS countries the population in 2006. Vestnik rossiyskogo onkologicheskogo nauchnogo tsentra im. N.N. Blokhina RAMN, 2008, vol. 19, pp. 52-57 (in Russ.).

2. Pearce T., Philips S., Brown J. et al. Bone metastases from prostate, breast and multiple myeloma: differences in lesion conspicuity at short inversion recovery and diffusion-weighted MRI. Br. J. Radiology, 2012, no. 85 (1016), pp. 1102-1106.

3. Clain C. The role of radiologic screening of lung cancer. Radiol. Clin. North. America, 1990, no. 28, pp. 489-495.

4. Tarynos K., Garcia O., Karr B. et al. A correlation study of bone scanning with clinical and laboratory findings in the staging of non-small-cell lung cancer. Clin. Nucl. Med, 1991, no. 16 (2), pp. 107-109.

5. Trufanov G.E., Ryazanov V.V., Dergunova N.I. et al. Sovmeshchennaya pozitronno-emissionnaya i komp’yuternaya tomografiya (PET/KT) v onkologii [Combined positron emission and computed tomography (PET/CT) in oncology]. Moscow, 2007. 127 p.

6. Laryukov A.V., Laryukova E.K. Beam diagnostic methods to assess the prevalence of peripheral NSCLC. Kazanskiy meditsinskiy zhurnal, 2015, vol. 96, no. 1, pp. 16-21 (in Russ.).

7. Trakhtenberg A.Kh., Frank G.N., Poddubnyy V.V. Diagnosis and treatment of large cell carcinoma lung. Rossiyskiy onkologicheskiy zhurnal, 2007, no. 3, pp. 4-8 (in Russ.).

8. Shavladze Z.N., Berezovskaya T.P., Neledov D.V. et al. Diagnosis of metastatic involvement of the skeleton in patients with breast cancer: a comparative evaluation of MRI and whole-body scintigraphy skeleton. Meditsinskaya vizualizatsiya, 2008, no. 3, pp. 105-116 (in Russ.).

9. Sergeev N.I., Fomin D.K., Kotlyarov P.M. et al. Comparative study opportunities bone scan and magnetic resonance imaging of the whole body in the diagnosis of bone metastases. Meditsinskaya vizualizatsiya, 2014, no. 4, pp. 107-113 (in Russ.).

10. Shiryaev S.V. Opyt primeneniya i perspektivy PET v onkologii [Experience of application and prospects of PET in oncology]. Luchevaya diagnostika i interventsionnaya radiologiya v klinicheskoy onkologii. Evropeyskaya shkola po onkologii. Moscow, 2006. Pp. 24-34.

11. Phelps M., Cherry S. The changing design of positron imaging systems. Clinical Positron Imaging, 1998, no. 1, pp. 31-45.