Metabolism of vitamin D and means of its main functions’ implementation
S.V. MALTSEV, G.Sh. MANSUROVA
Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012
Maltsev S.V. — D. Med. Sc., Professor, Head of the Department of Pediatrics with a course in Polyclinic Pediatrics, tel. (843) 236-20-84, e-mail: maltc@mail.ru
Mansurova G.Sh. — Cand. Med. Sc., Associate Professor of the Department of Pediatrics with a course in Polyclinic Pediatrics, tel. +7-917-390-79-20, e-mail: gsm98@mail.ru
The article presents a review of literature on the issue of vitamin D metabolism and its functions. The authors discuss the vitamins D2 and D3 transformations in the organism, the role of vitamin D-binding protein and the vitamin D receptors, the genetic and non-genetic effects of calcitriol which determine its various functions. The role of bile and fatty acids in the process of vitamin D absorption is shown, as well as the connection of vitamin D with phosphate-calcium metabolism.
Key words: vitamin D, 25(ОН)D, calcitriol, 1,25(OH)2D, vitamin-D-binding protein, vitamin D receptors.
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