S.A. BELOV, F.A. KHABIROV, G.M. SHARAFUTDINOVA, B.E. GUBEEV, M.V. ELISTRATOVA

 KSMA — branch campus of the FSBEI FPE RMACPE MOH Russia, Kazan

Contact details:

Belov S.А. — postgraduate student of the Department of Neurology

Address: 36 Butlerov St., 420012 Kazan, Russian Federation, tel.: +7 (843) 233-34-91, e-mail: 13btfkdarky@mail.ru

The article describes the main mechanisms of sleep disorders in multiple sclerosis. Multiple sclerosis (MS) is a disabling disease of the central nervous system. The incidence of MS is increasing worldwide, which has significant socioeconomic consequences. Relapsing-remitting MS (RRMS), characterized by relapses with stable neurological disability between episodes, primary progressive MS (PPMS) with a progressive course from the beginning, and secondary progressive MS (SPMS) with a progressive course after an initial relapsing-remitting course, are the phenotypes of multiple sclerosis. In all MS variants, in addition to visual and sensory disorders, pareses, pain, depression and anxiety, bladder problems, and cerebellar dysfunction, cognitive dysfunction and sleep disorders are also the most common clinical manifestations. Sleep disorder is a general term that refers to a wide range of symptoms and disorders related to sleep, including insomnia, restless legs syndrome, sleep apnea, narcolepsy and a sleep behavior disorder — REM (rapid eye movement). Poor sleep quality and insufficient sleep during adolescence may increase the risk of multiple sclerosis. Sleep disorders are a common manifestation in patients with multiple sclerosis, even in patients with low levels of disability. People with multiple sclerosis often experience poor sleep quality, restless legs syndrome, and insomnia.

Key words: multiple sclerosis, sleep disorders, sleep mechanisms, restless legs syndrome, insomnia, cognitive functions

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