A.A. NIGMATYANOVA^1,2, R.Z. ABDRAKIPOV², E.V. SUKHORUKOVA², M.A. AFANASYEVA², S.A. LAPSHINА^1,2, M.S. PROTOPOPOV^1,2, A.M. GARIFULLINA¹

¹Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

²Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

Nigmatyanova A.A. — doctor-ordinator of the Department of hospital therapy, tel. (843) 237-34-83, e-mail: anzilya-s@yandex.ru

Abdrakipov R.Z. — head of the rheumatology department, tel. (843) 231-21-67, e-mail: rkb_nauka@rambler.ru

Sukhorukova E.V. — doctor rheumatology department, tel. (843) 231-21-67, e-mail: s-elena1407@mail.ru

Afanasyev M.A. — doctor rheumatology department, tel. (843) 231-21-67, e-mail: afmaria2108@mail.ru

Lapshin S.A. — Cand. Med. Sc., Associate Professor of the Department of hospital therapy, tel. (843) 237-34-83, e-mail: svetlanalapshina@mail.ru

Protopopov M.S. — Cand. Med. Sc, Assistant of the Department of Hospital Therapy, tel. (843) 231-21-67, e-mail: mikhailprotopopov@gmail.com

Garifullina A.M. — doctor-ordinator of the Department of Hospital Therapy, tel. (843) 237-34-83, e-mail: g_adelya@bk.ru

Adult Still’s disease — is a systemic inflammatory disease characterized by lesions of the joints, high fever, skin rash and neutrophilic leukocytosis in the absence of seropositivity for rheumatoid factor and antibodies to cyclic citrullinated. Clinical manifestations of Still’s disease diverse spectrum of diseases in the differential diagnosis is very broad and includes infection neoplastichekie and autoimmune diseases. Clinical examples with the analysis of the clinical manifestations of the disease, diagnostic criteria and treatment strategies.
Key words: adult Still’s disease, the symptoms, the criteria for treatment.

REFERENCES

1. Yamaguchi M., Ohta A., Tsunematsu T, et al. Preliminary criteria for classification of adult Still’s disease. J Rheumatol, 1992, 19, rr. 424-30.
2. Klinicheskie rekomendatsii. Revmatologiya. 2-e izd., ispravl. i dop.; pod red. E.L. Nasonova [Clinical practice guidelines. Rheumatology. 2nd ed., Corrected. and additional. Ed. by E.L. Nasonov]. Moscow, 2001. 738 p.
3. Gulyaev S., Novikov P., Rozina T. Still’s disease adults with severe liver disease. Vrach, 2013, May, no. 5, pp. 20-28 (in Russ.).
4. Murav’ev Yu.V., Nasonov E.L. Still’s disease that developed in adults. Nauchno-prakticheskaya revmatologiya, 2011, no. 2, pp. 58-65 (in Russ.).
5. Titova I.P. Still’s syndrome in adults: clinical features, diagnosis, treatment. Meditsinskiy zhurnal, 2002, no. 2, pp. 37-44 (in Russ.).