S.A. TUPIKOVA¹, L.I. ZAKHAROVA²

¹M.I. KalininSamara Regional Hospital, 159 Tashkentskaya St., Samara, Russian Federation

²Samara State Medical University, 89 Chapaevskaya St., Samara, Russian Federation 443099

Tupikova S.A. — post-graduate student of the Department of children’s diseases, head of the division, tel. +7-927-264-55-77, e-mail: tvv@63.ru¹

Zakharova L.I. — D. med. Sc., Professor of the Department of children’s diseases, tel. +7-960-816-28-20, e-mail: kdbsamgmu@jandex.ru²

The article presents data abaut 46 small premature infants on 22-34 weeks of gestation, of which 27 children had subependymal hemorrhage (SEH) in the first three days of life. Were defined gestational characteristics of indicators of cerebral blood flow and vascular-platelet hemostasis in the dynamics of an early neonatal period. Simulation of hyper perfusion in the areas of anterior and posterior cerebral arteries at a time of reduced flow in v. Haleni was found; with low level of plasmatic fibronectin and platelet aggregation activity mediates it causes the development of SEH.

Key words: small premature infants, neurosonography and Doppler sonography of cerebral blood vessels, fibronectin, platelet aggregation activity.

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