L.A. BALYKOVA¹, S.A. IVYANSKIY¹, Yu.O. SOLDATOV², A.A. SHIROKOVA¹, N.V. SHCHЕKINA², A.N. URZYAEVA¹

¹Medical Institute of Mordovia State University, 26a Ulyanov St., Saransk, Russian Federation, 430032

²Mordovia Republican Clinical Children’s’ Hospital, 15 Rosa Luxemburg St., Saransk, Russian Federation, 430032

Balykova L.A. — D. Med. Sc., Professor, Head of the Department of Pediatrics, tel. (8342) 32-19-83, e-mail: larisabalykova@yandex.ru

Ivyanskiy S.A. — Cand. Med. Sc., Associate Professor of the Department of Pediatrics, tel. (8342) 35-30-02, e-mail: stivdoctor@yandex.ru¹

Soldatov Yu.O. — Cand. Med. Sc., Head of the Department of Functional Diagnostics, tel. (8342) 32-12-68, e-mail: soldatovyu@yandex.ru

Shirokova A.A. — postgraduate student of the Department of Pediatrics, tel. (8342) 35-30-02, e-mail: shirockova@inbox.ru

Shchekina N.V. — Head of the Department of Cardiology, tel. (8342) 35-32-15, e-mail: nvschekina@mail.ru

Urzyaeva A.N. — postgraduate student of the Department of Pediatrics, tel. (8342) 35-30-02, e-mail: anna1868601@mail.ru

The article presents the results of comparative, randomized, parallel-group clinical trial of L-carnitine in young athletes. It was established that L-carnitine increases adaptation to physical stress and has a pronounced therapeutic effect in athletes with stress-induced cardiomyopathy, reducing the representation of potentially dangerous ECG disorders, severity of benign ECG abnormalities and hemodynamic changes, lowering the concentration of biochemical markers of myocardial damage. A significant reduction in symptoms of cardiac remodeling was observed in 75% and a slight reduction in 25% of patients. It has been shown that L-carnitine improves natural and adaptive immunity, and thus helps to reduce seasonal morbidity and omissions of sports activities. Authors make a conclusion about the feasibility of the use of L-carnitine in sports practice, especially if signs of myocardial remodeling or dysfunction of immunity are present.

Key words: L-carnitine, stress cardiomyopathy, immunity, young athletes.

 

 

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