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  • Intraoperative identification of the parathyroid glands in a patient with tertiary hyperparathyroidism (clinical case)

    Редактор | 2023, Clinical case, Practical medicine part 21 №2. 2023 | 18 марта, 2023

    I.Z. GALIEV, S.V. ZINCHENKO, E.YU. MINGALIMOVA

     Kazan (Volga Region) Federal University, Kazan

    Republic Clinical Oncology Dispensary, Kazan

     Contact details:

    Galiev I.Z. — Senior Lecturer of the Department of Surgery, Obstetrics and Gynecology

    Address: 29 Sibirskiy tract, Kazan, Russian Federation, 420088, tel.: +7-951-063-31-78, e-mail: galiev-i-1990@mail.ru

     The problem of diagnosing and treatment of secondary and tertiary hyperparathyroidism has not lost its relevance to date. Radical removal of transformed parathyroid glands with simultaneous free replantation of the unchanged part ensures the restoration of phosphorus-calcium metabolism. The issues of removal with subsequent autologous transplantation of parathyroid glands are associated with a number of difficulties for specialists: small size (less than 6 x 3 x 1.5 mm) and similarity with surrounding tissues.

    This paper shows the effectiveness of the use of 5 ALA derivatives for fluorescent imaging of hyperplastic and adenomatous transformed parathyroid glands in a patient with tertiary hyperparathyroidism. Visualization of the parathyroid glands before surgical treatment was not carried out in full due to the severity of the patient’s condition and the presence of contraindications for iodine contrast studies.

    Key words: tertiary hyperparathyroidism, fluorescent diagnostics, parathyroid gland, parathyroidectomy.

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    9. Chissov V.I., Reshetov I.V., Golubtsov A.K., Filonenko E.V., Sevryukov F.E., Krekhno O.P., Kirpa E.A. Sposob intraoperatsionnogo opredeleniya parashchitovidnykh zhelez, no. 2458689; zayavl. 28.03.2011; opubl. 20.08.2012, Byul. no. 21 [A method for intraoperative determination of the parathyroid glands. no. 2458689; dec. 03/28/2011; publ. 20.08.2012, Bull. no. 21].
    10. Zinchenko S.V., Galiev I.Z., Minabutdinov R.M., Aliev I.G., Bilyalov A.I., Vakhitova R.Sh. Sposob intraoperatsionnoy identifikatsii giperplazii i opukholey parashchitovidnykh zhelez u patsientov s pervichnym, vtorichnym i tretichnym giperparatireozom dlya adekvatnoy paratireoidektomii, no. 2019142608; zayavl. 28.03.2011; opubl. 23.06.2020, Byul. no. 18 [A method for intraoperative identification of hyperplasia and tumors of the parathyroid glands in patients with primary, secondary and tertiary hyperparathyroidism for adequate parathyroidectomy. no. 2019142608; dec. 03/28/2011; publ. 06/23/2020, Bull. no. 18].

    Метки: 2023, E.YU. MINGALIMOVA, fluorescent diagnostics, I.Z. GALIEV, parathyroid gland, parathyroidectomy, Practical medicine part 21 №2. 2023, S.V. ZINCHENKO, tertiary hyperparathyroidism

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