V.B. TSKHAY

 Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Krasnoyarsk

Contact details:

Tskhay V.B. — MD, Professor, Head of the Department of Perinatology, Obstetrics and Gynecology

Address: 2A/1 Akademika Kirenskogo St., Krasnoyarsk 660074, Russian Federation, tel.: +7-923-287-21-34, e-mail: tchai@yandex.ru

 Female health and the reproductive tract microbiota are closely associated. Current data indicate that changes in the intestinal and/or different levels of the female reproductive tract microbiota composition can be used prognostically as a diagnostic tool for the disease, and a number of microorganisms can be «markers» for assessing its form and prevalence. Studies of the reproductive organs microbiota cover both the vagina and cervical canal, and the upper parts of the reproductive organs. The endometrium in women contains microbiota consisting of various microorganisms.

The purpose was to evaluate the latest discoveries in the microbiota role in the adenomyosis pathogenesis. In an attempt to clarify the relationship between adenomyosis and the reproductive organs microbiota, we analyzed 2020–2025 publications from PubMed and eLIBRARY databases using the keywords «adenomyosis», «intestinal microbiota», «vaginal microbiota», «endometrial microbiota», and «pathogenesis».

Conclusion. Adenomyosis is closely associated with bacterial dysbiosis of the endometrium. Potential changes in the microbial environment of the endometrium can contribute to the adenomyosis development. The study of the microbiota composition in women with adenomyosis seems to be a fairly new and very promising direction, both from a scientific and practical point of view.

Key words: adenomyosis, intestinal microbiota, vaginal microbiota, endometrial microbiota.

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