E.V. ORLOVA, N.P. LYAMINA, N.V. SKOROBOGATYTH, I.V. POGONCHENKOVA

Moscow Centre for Research and Practice in Medical Rehabilitation, Restorative and Sports Medicine, Moscow

Contact details:

Orlova E.V. — MD, Chief Researcher of the Department of Medical Rehabilitation

Address: 53 Zemlyanoy Val St., building 1, Moscow, Russian Federation, 105120, tel.: +7 (495) 706-69-48, e-mail: yevorlova@mail.ru

The purpose — to evaluate the clinical efficiency of the individually dosed interval hypoxic-hyperoxic therapy in the medical rehabilitation of patients with osteoarthritis (OA).

Material and methods. 68 patients with OA (81% females, aged 44 to 69 years) were included in the randomized controlled study. 35 study group patients received 10 hypoxic-hyperoxic therapy procedures, 33 control group patients – only standard rehabilitation. The study group patients were breathing hypoxic (FiO₂ 13–15%) and hyperoxic (FiO₂ up to 40%) gas mixture through a mask in the interval mode using ReOxy device. The duration of 1–4 procedures was 30 min, 5–10 procedures — 40 min. The patients of both groups underwent a 2-week standard rehabilitation program: 10 group sessions of physical exercises, 10 procedures of magnetic therapy for joints, 10 sodium chloride baths.

Results. After 2 weeks, joint pain on a 100 mm visual analog scale in the study group decreased by 54% (p < 0.01), Lequesne index — by 35.7% (p < 0.05), WOMAC index — by 49.6% (p < 0.05), Spielberger — Khanin reactive anxiety test — by 30.1% (p < 0.05), depression symptoms by Beck depression inventory — by 60.8% (p < 0.01). In the study group there were statistically significant differences from the control group in all parameters (р < 0.05).

Conclusion. The 2-week rehabilitation program, including interval hypoxic-hyperoxic therapy, reduces pain, depression and reactive anxiety symptoms, improves functional status in patients with OA.

Key words: osteoarthritis, rehabilitation, hypoxic-hyperoxic therapy, individually dosed interval hypoxia, hypoxic conditioning.

 (For citation: Orlova E.V., Lyamina N.P., Skorobogatyth N.V., Pogonchenkova I.V. Interval hypoxic-hyperoxic therapy in complex rehabilitation of patients with osteoarthritis. Practical medicine. 2022. Vol. , № , P.)