V.N. DIOMIDOVA^{1, 2, L}.V. TARASOVA¹, D.I. TRUKHAN³, Yu.V. TSYGANOVA¹, V.S. VINOGRADOVA¹

¹Ulyanov Chuvash State University, 15 Moskovskiy prospekt, Cheboksary, Russian Federation, 428015

²City Clinical Hospital No. 1, 46 Traktorostroiteley prospekt, Cheboksary, Russian Federation, 428028

³Omsk State Medical University, 12 Lenin Str., Omsk, Russian Federation, 644099

Diomidova V.N. — D. Med. Sc., Head of Propedeutics of the Department of Internal Diseases with a course of Radiation Diagnostics, tel. (8352) 45-26-17, e-mail: diomidovavn@rambler.ru

Tarasova L.V. — D. Med. Sc., Head of the Department of Faculty and Hospital Therapy, tel. (8352) 45-26-17, e-mail: tlarisagast18@mail.ru

Trukhan D.I. — D. Med. Sc., Professor of the Department of Internal Medicine and Outpatient Therapy, tel. (3812) 74-44-27, e-mail: dmitry_trukhan@mail.ru.

Tsyganova Yu.V. — post-graduate student of the Department of Faculty and Hospital Therapy, tel. (8352) 45-26-17

Vinogradova V.S. — post-graduate student of the Department of Propedeutics of Internal Diseases with a course of Radiation Diagnostics, tel. (8352) 45-26-17

In order to establish the elastometric values of the hepatic parenchyma stiffness during nonalcoholic fatty liver disease (NAFLD), according to elastometry and elastography data, 30 patients (mean age 41.1±2.7 y.o.) with NAFLD were examined with a shear wave. One-dimensional (transient) elastometry of the liver (Fibroscane, Echo-Sens, France) and two-dimensional shear wave elastography with elastometry (Aixplorer, Supersonic Imagine, France) were performed. The liver stiffness with steatosis in NAFLD patients, according to the values of the median E_mean was 11.2 kPa (2.5-97.5^thpercentile — 8.3–12.6 kPa), E_max — 27.8 (23.2-33.1) kPa, and SD — 3.0 (1.8–3.5) kPa. It was found that the informative value of one-dimensional and two-dimensional elastography by shear wave in determining the liver stiffness under NAFLD was higher in case of their combined use (sensitivity, specificity and accuracy reached 94.0%, 97.8%, 94.9%, respectively).

Key words: shear wave elastography, ultrasound examination, liver, nonalcoholic fatty liver disease.

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