N.R. KHASANOV¹, O.S. BELKOREY²

¹Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

²City polyclinic №218, 8 Shokalskiy St., Moscow, Russian Federation, 129642

Khasanov N.R. — D. Med. Sc., Professor of the Department of Propedeutics of Internal Diseases, tel. +7-987-290-60-21, e-mail: ybzp@mail.ru

Belkorey O.S. — cardiologist, tel. +7-916-044-36-68, e-mail: cardiosvao@gmail.com

The study was aimed at investigation of the influence of the factors of cardiovascular risk, and the glomerular filtration rate (GFR) on cardiovascular complications in patients with acute myocardial infarction. The retrospective study included 179 patients admitted to hospitals in Moscow with verified diagnosis of acute myocardial infarction (AMI). Among the risk factors of AMI the most prevalent were: arterial hypertension (AH), smoking and diabetes mellitus (DM). The risk of early post-infarction angina increased 14-fold in patients with a decrease in GFR less than 59 mL/min / 1.73 m² (OR=13.9, 95% CI=4,23-45,65; p=0001). With reduction of GFR less than 29 mL/min / 1.73 m² increased frequency of atrial fibrillation (AF). In the group of patients with AF compared with AMI patients with sinus rhythm, significantly more frequently was the renal dysfunction, an early post-infarction angina and acute left ventricular aneurysm. In patients with acute myocardial infarction in the presence of AF risk of hospital complications significantly increased in 10 times (OR 10.27, 95% CI 2,58-40,9; p=0.001).

Key words: acute myocardial infarction, factors of cardiovascular risk, glomerular filtration rate.

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