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  • Importance of microbiological analysis for rational antibacterial therapy in urology department of in-patient hospital of high-tech medical care

    Редакция | 2014, Original articles, Practical medicine 03 (14) Modern questions of diagnostics | 15 июля, 2014

    D.A. KIREEV1,2, D.V. PISANENKO1, A.A. DANILOV2, D.V. ABRAMOV2, M.V. KHAZOV2, S.V. ROMANOV2, O.V. RUINA1,2, A.B. STROGANOV1,2

    1Nizhny Novgorod State Medical Academy, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, Russian Federation 603005

    2Volga District Medical Center of Federal Medical and Biological Agency of the Russian Federation, 14 Ilinskaya St., Nizhny Novgorod, Russian Federation 603109

    Kireev D.A. — hospital physician of the Department of surgical pathology, tel. (831) 421-69-77, e-mail: kel-el@yandex.ru1,2

    Pisanenko D.V. — postgraduate student of the Department of clinical pharmacology,
    tel. +7-902-784-08-63, e-mail: mustang21053@gmail.com1

    Danilov A.A. — Head of Urology Department № 1, tel. (831) 421-69-76, e-mail: remyan@mail.ru2

    Abramov D.V. — Head of Urology Department № 2, tel. (831) 421-69-77, e-mail: abramov-pomc@mail.ru2

    Khazov M.V. — Head physician of clinical hospital № 1 of Federal Budgetary Institution of Health Care of Volga District Medical Centre (VDMC) under Federal Medical and Biological Agency (FMBA) of Russian Federation, tel. (831) 428-81-88, e-mail: hazov -pomc@mail.ru2

    Romanov S.V. — Cand. Med. Sc., Assistant Professor, Head of Federal Budgetary Institution of Health Care of Volga District Medical Centre (VDMC) under Federal Medical and Biological Agency (FMBA) of Russian Federation, tel. (831) 428-81-88, e-mail: romanov-pomc@mail.ru2

    Ruina O.V.— Cand. Med. Sc., clinical pharmacologist of Volga District Medical Centre (VDMC) under Federal Medical and Biological Agency (FMBA) of Russian Federation, tel. (831) 421-69-64, e-mail: olga-ru1@yandex.ru1,2

    Stroganov A.B. — D. Med. Sc., Assistant Professor of the Department of Surgical Pathology, tel. +7-903-601-18-49, e-mail: ab-stroganov@yandex.ru1,2 

    The article provides an analysis of microbiologic picture of 2,700 patients with various urological pathology receiving treatment in a high-tech medical care hospital. The main operational interventions are featured. Rational antibiotic therapy and preventive antibiotics were considered.

    Key words: localized microbiological monitoring, urology, antibiotic therapy.

     


    REFERENCES

    1. Foxman B. The epidemiology of urinary tract infection. Nat. Rev. Urol. 2010, Dec., no. 7 (12), pp. 653-660.

    2. Schito G.C., Naber K.G., Botto H. et al. The ARESC study: an international survey on the antimicrobial resistance of pathogens involved in uncomplicated urinary tract infections. Int. J. Antimicrob. Agents, 2009, no. 34, pp. 407-413.

    3. Franco A.V. Recurrent urinary tract infections. Best Pract. Res. Clin. Obstet. Gynaecol., 2005, no. 19, pp. 861-873.

    4. Prakticheskoe rukovodstvo po antiinfektsionnoy khimioterapii [Practical guidance on anti-infective chemotherapy, Ed. L.S. Stratchounski, Y.B. Belousov, S.N. Kozlov]. Smolensk: IACMAC, 2007. 464 p.

    5. Savelyev V.S., B.R. Gelfand, Yakovlev S.V. Strategy and tactics of antimicrobial agents in hospitals in Russia. Russian national recommendations [Strategiya i taktika primeneniya antimikrobnykh sredstv v lechebnykh uchrezhdeniyakh Rossii. Rossiyskie natsional’nye rekomendatsii]. Moscow, 2012. 96 p.

    6. Grabe M. (chairman), Bjerklund-Johansen T.E., Botto H. et al. Guidelines on Urological Infections. European Association of Urology, 2013, no. 3, p. 106.

    7. European Committee for Antimicrobial Susceptibility Testing (EUCAST) of the European Society of Clinical Microbiology and Infectious Dieases (ES MID). EUCAST Definitive Document E.DEF 3.1, June 2000: Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by agar dilution. Clin. Microbiol. Infect., 2000, no. 6 (9), pp. 509-515.

    8. Perepanova T.S., Hazan P.L. Uncomplicated urinary tract infection. Ginekologiya, 2009, no. 5, pp. 40-44 (in Russ.).

    9. European Committee for Antimicrobial Susceptibility Testing (EUCAST) of the European Society of Clinical Microbiology and Infectious Dieases (ESCMID). EUCAST Definitive Document E. Def 1.2, May 2000: Terminology relating to methods for the determination of susceptibility of bacteria to antimicrobial agents. Clin. Microbiol. Infect., 2000, no. 6 (9), pp. 503-508.

    10. Perepanova T.S., R.S. Kozlov, Dehnich A.V. etc. The choice of antimicrobial drugs for urinary tract infections. Urologiya, 2012, no. 2, pp. 4-8 (in Russ.).

    11. Zaitsev A.V., Perepanova T.S., Kozlov R.S. Russian and other international epidemiological study of the results of clinical aspects and antimicrobial resistance of pathogens cystitis in women (ARESC): value for empirical therapy. Urologiya, 2011, no. 2, pp. 30-36 (in Russ.).

    12. Naber K.G., Schito G., Botto H. et al. Surveillance study in Europe and Brazil on clinical aspects and Antimicrobial Resistance Epidemiology in Females with Cystitis (ARESC): implications for empiric therapy. Eur. Urol. Nov., 2008, no. 54 (5), pp. 1164-1175.

    13. Falagas M.E., Vouloumanou E.K., Togias A.G. et al. Fosfomycin versus other antibiotics for the treatment of cystitis: a meta-analysis of randomized controlled trials. J. Antimicrob. Chemother., 2010, no. 65 (9), pp. 1862-1877.

    14. Beerepoot M.A., ter Riet G., Nys S., et al. Cranberries vs antibiotics to prevent urinary tract infections: a randomized double-blind noninferiority trial in premenopausal women. Arch. Intern. Med., 2011, no. 171 (14), pp. 1270-1278.

    Метки: A.A. DANILOV, A.B. STROGANOV, antibiotic therapy, D.A. KIREEV, D.V. ABRAMOV, D.V. PISANENKO, localized microbiological monitoring, M.V. KHAZOV, O.V. RUINA, Practical medicine 03 (14) Modern questions of diagnostics, S.V. ROMANOV, urology

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