T.A. MARTYNOVA¹, N.I. MAKSIMOV², R.M. VALEEVA²

¹Republic Clinical-Diagnostic Center, 87b Lenin Str., Izhevsk, Russian Federation, 426009

²Izhevsk State Medical Academy, 281 Kommunarov Str., Izhevsk, Russian Federation, 426034

Martynova T.A. — cardiologist, Assistant Lecturer of the Department of Hospital Therapy with the courses of Cardiology and Functional Diagnostics, e-mail: tatyana_martynova@list.ru

Maksimov N.I. — Doc. Med. Sc., Professor, Head the Department of Hospital Therapy with the courses of Cardiology and Functional Diagnostics, e-mail:maxni@list.ru,

Valeeva R.M. — Cand. Med. Sc., Associate Professor of the Department of Hospital Therapy with the courses of Cardiology and Functional Diagnostics,

The article present the results of retrospective studies of 201 patients with acute coronary syndrome, an assessment of clinic, laboratory, instrumental study and electrokinetic properties of red blood cells. The patients were divided into two groups: patients with ST-segment elevation on ECG (110 patients) and patients without ST-segment elevation on ECG (91 patients). Multivariate analysis showed an individual set of traits for each group associated with electrokinetic parameters of erythrocytes.

Key words: acute coronary syndrome, risk factors, electrokinetic properties parameters of erythrocytes.

(For citation: Martynova T.A., Maksimov N.I., Valeeva R.M. Impact of electrokynetic parametrs of red blood cells on risk factors of cardiovascular diseases in patients with acute coronary syndrome. Practical Medicine. 2018)

REFERENCES

1. Aronov D.M., Lupanov V.P. Some aspects of the pathogenesis of atherosclerosis. Ateroskleroz i dislipidemii, 2011, no. 1, pp. 48–56 (in Russ.).
2. Kozinets G.I., Popova O.V., Budnik M.I. Ehlektricheskiy zaryad kletok krovi: Laboratorno-klinicheskoe znachenie [Electric charge of blood cells: laboratory and clinical significance]. Moscow: Prakticheskaya meditsina, 2007. 207 p.
3. Krylov V.N., Deryugina A.V., Antipenko E.A. Typical changes in the electrophoretic mobility of erythrocytes and their phospholipid composition in various diseases. Klinicheskaya laboratornaya diagnostika, 2009, no. 9, pp. 37–40 (in Russ.).
4. AlMomani T.D., Vigmostad S.C., Chivukula V.K., Al-Zube L., Smadi O., BaniHani S. Red blood cell flow in the cardiovascular system: a fluid dynamics perspective. Critical Reviews in Biomedical Engineering, 2012, no. 40 (5), pp. 427–440.
5. Makhneva A.V. Age-related features of the state of the erythrocyte cell membranes in patients with coronary heart disease. Vestnik RGMU, 2011, no. 3, pp. 76–79 (in Russ.).
6. Solovʹev A.A, Golendukhin A.N., Kutyavina S.V., Nikitin E.N. Sposob mikroehlektroforeza kletok krovi i ehpiteliotsitov i ustroystvo dlya ego osushchestvleniya. Zaregistrirovano v Gosudarstvennom reestre izobreteniy RF 27.05.2001 za no. 2168176 [The method of microelectrophoresis of blood cells and epithelial cells and device for its implementation. Registered in the State Register of Inventions of the Russian Federation on May 27, 2001, No. 2168176].
7. Sukhenko E.P., Lisitsyn N.B., Palagin V.A. Electrophoretic Cellular Analysis Using the Cyto-Expert Instrument Complex. Klinicheskaya laboratornaya diagnostika, 2011, no. 11, pp. 35–38 (in Russ.).
8. Solov’ev A., Shishkin A., Kiryanov N. Cytoanalytical complex of new generation “cyto-expert”: its opportunities and prospects. Regional Innovations, 2017, 4, pp. 43–45.
9. Mitina O.V., Mikhaylovskaya I.B. Faktornyy analiz dlya psikhologov [Factor analysis for psychologists]. Moscow: Uchebno-metodicheskiy kollektor «Psikhologiya», 2001. 169 p.