Z.Kh. KURYAZOVA

 Tashkent State Stomatology Institute, 103 Makhtumkuli Str., Tashkent, Republic of Uzbekistan, 7000033

 Kuryazova Z.Kh. ― PhD (medicine), Associate Professor of the Department of Ophthalmology, Otolaryngology and Gynecology, e-mail: kuryazova_z@mail.ru

 The frequency of Demodex folliculorum detection in patients with inflammatory diseases of the anterior segment of the eyes is 52.8%. In patients with eye demodecosis, disorders of cellular (decrease in CD4 + cell count and increase in CD8 + lymphocyte content) and humoral (decrease in B-lymphocyte and IgA, IgG, IgM) immunity are detected, which are characteristic for secondary immunodeficiency state. In the lacrimal fluid, a significant increase in the content of IgG and IgM is observed. Local use of “Fensulkal” drug in the treatment of 78 patients (156 eyes) allowed stopping the inflammatory process in the meibomian glands caused by mites, helped improve the immunograms, shortened the treatment period by 5-10 days.

Key words: demodecosis of eyes, cellular and humoral immunity, local immunity, treatment.

 (For citation: Kuryazova Z.Kh. Immunological aspects of the eye demodecose. Practical Medicine. 2018)

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