Immuno-genetic determinacy in renal allograft recipients
A.R. MAKSEYEV2, M.I. KHASANOVA1,3, R.F. KHAKIMOVA2, Sh.R. GALEYEV1,3, K.V. SITKINA1,3
1Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064
2Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012
3Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012
Makseyev A.R. — postgraduate student of the Department of Clinical Immunology and Allergology, tel. +7-917-924-00-89, e-mail: alfiz.mar82@inbox.ru
Khasanova M.I. — Cand. Med. Sc., Associate Professor of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-903-307-67-32, e-mail: milyash@ inbox.ru
Khakimova R.F. — D. Med. Sc., Professor of the Department of Clinical Immunology and Allergology, tel. +7-937-285-75-38, e-mail: Khakimova@yandex.ru
Galeev Sh.R. — Cand. Med. Sc., Associate Professor of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-917-237-16-50, e-mail: samil80@bk.ru
Sitnikova K.V. — Cand. Med. Sc., Assistant of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-987-412-18-45, e-mail: Kseniy_sit@mail.ru
The aim of this study was to investigate the association of antigens of HLA class I (A, B, C) and blood group antigens (AB0), Rh with clinical phenotype in kidney recipients with CKD of various etiologies. The findings suggest that there is immunogenetic determinacy exists in patients with end-stage chronic renal failure which had developed as a result of chronic glomerulonephritis, diabetic nephropathy, and various congenital anomalies of the kidney.
Key words: immune genetic determinacy, human leukocyte antigen (HLA), kidney transplantation, chronic renal failure.
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