A.R. MAKSEYEV², M.I. KHASANOVA^1,3, R.F. KHAKIMOVA², Sh.R. GALEYEV^1,3, K.V. SITKINA^1,3

¹Republican Clinical Hospital of the MH of RT, 138 Orenburgskiy Trakt, Kazan, Russian Federation, 420064

²Kazan State Medical University, 49 Butlerov St., Kazan, Russian Federation, 420012

³Kazan State Medical Academy, 36 Butlerov St., Kazan, Russian Federation, 420012

Makseyev A.R. — postgraduate student of the Department of Clinical Immunology and Allergology, tel. +7-917-924-00-89, e-mail: alfiz.mar82@inbox.ru

Khasanova M.I. — Cand. Med. Sc., Associate Professor of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-903-307-67-32, e-mail: milyash@ inbox.ru

Khakimova R.F. — D. Med. Sc., Professor of the Department of Clinical Immunology and Allergology, tel. +7-937-285-75-38, e-mail: Khakimova@yandex.ru

Galeev Sh.R. — Cand. Med. Sc., Associate Professor of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-917-237-16-50, e-mail: samil80@bk.ru

Sitnikova K.V. — Cand. Med. Sc., Assistant of the Department of Urology and Nefrology, doctor of Kidney Transplantation Department, tel. +7-987-412-18-45, e-mail: Kseniy_sit@mail.ru

The aim of this study was to investigate the association of antigens of HLA class I (A, B, C) and blood group antigens (AB0), Rh with clinical phenotype in kidney recipients with CKD of various etiologies. The findings suggest that there is immunogenetic determinacy exists in patients with end-stage chronic renal failure which had developed as a result of chronic glomerulonephritis, diabetic nephropathy, and various congenital anomalies of the kidney.

Key words: immune genetic determinacy, human leukocyte antigen (HLA), kidney transplantation, chronic renal failure.

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