I.N. KONONOVA

Ural State Medical University, 3 Repin St., Ekaterinburg, Russian Federation, 620028 

Kononova I.N. ― Cand. Med. Sc., Associate Professor of the Department of Obstetrics and Gynecology, tel. +7-904-382-41-16, e-mail: irkon@el.ru 

The study of the immune and psychological status of 306 patients with CIN revealed a relationship between psychological misadaption, immune dysfunctions and the degree of cervical dysplasia. Introduction of an immunomodulating medication Imunofan to a complex therapy contributed to the normalization of local immunity, acceleration of reparative processes in cervix, which allows us to recommend this method in complex treatment of CIN.

Key words: immune status, psychological status, cervical intraepithelial neoplasia.

REFERENCES

1. Profilaktika raka sheyki matki: sb. nauch. tr., pod red. G.T. Sukhikh, V.N. Prilepskoy [Prevention of Cervical Cancer: Sat. scientific. proceedings. Ed. by G.T. Dry, V.N. Prilepskaya]. Moscow: MEDpress-inform, 2012. 190 p.

2. Oboskalova T.A., Kononova I.N., Sevost’yanova O.Yu., Berzin S.A. Epidemiological features of cervical cancer in women living in a large industrial city. Ural’skiy meditsinskiy zhurnal, 2014, no. 4 (118), pp. 69-72 (in Russ.).

3. Kononova I.N., Voroshilina E.S. Features local immunity in cervical intraepithelial neoplasia associated with HPV infection. Rossiyskiy immunologicheskiy zhurnal, 2014, vol. 8 (17), no. 3, pp. 809-811 (in Russ.).

4. Kononova I.N., Rogacheva T.V. The problem of the clinical and psychological support of patients with cervical pathology. Meditsinskaya psikhologiya v Rossii, 2015, no. 1 (30) (in Russ.), available at: http://mprj.ru

5. Gizinger O.A., Kononova I.N., Letyaeva O.V. Cervical neoplasia associated with HPV infection: complex therapy. Vrach, 2014, 12, pp. 70-73 (in Russ.).