R.R. LUKAEV¹, I.G. TRUKHANOVA²

¹Samara State Medical University, Department of Resuscitation and Intensive Therapy of Clinics, 165b Karl Marx Str., Samara, Russian Federation, 443079

²Samara State Medical University, 89 Chapayevskaya Str., Samara, Russian Federation, 443099

  Lukaev R.R. —  anesthesiologist, resuscitation specialist, tel. +7-917-151-45-11, e-mail: rinat-rean2009@yandex.ru

Trukhanova I.G. —  D. Med. Sc., Professor, Head of the Department and Clinic of Anesthesiology, Resuscitation and Emergency Medical Aid, tel. +7-927-651-23-65, e-mail: innasmp@yandex.ru

The article presents the results of examination of 47 patients diagnosed “HFRS, severe course, oliguria” on the first day after admission to the Infectious Diseases Department. Blood biochemical parameters and breakout C-reactive protein marker were analyzed. The state of cardiovascular system was examined using impedance cardiography. An increase in systemic vascular resistance and an increased amount of intrathoracic fluid were observed, as well as the decline of O₂ transport. To assess the impact of secondary bacterial infections on the central hemodynamics condition, a statistic analysis was performed with the estimation of C-reactive protein correlation with the changes of hemodynamic parameters. The factors were determined which impair gas exchange and blood supply of tissues with subsequent worsening of the disease.

Key words: HFRS, cardiovascular system, C-reactive protein, impedance cardiography.

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